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Opportunité en vedette

Underwater "Superglue"

University of Waterloo

BackgroundIn adhesion science, water or moisture has traditionally been treated as surface contaminants or weak boundary layers, since they deteriorate adhesives through a variety of complex mechanisms including erosion, plasticization, swelling, and hydrolysis of adhesive polymers. Contrary to the difficulties faced by man, in the sea, there is a variety of marine organisms capable of adhering to all type of wet surfaces including mussels that stick firmly on rocks, sandcastle worms that...
Opportunité en vedette

Room Temperature Plasmontronic Devices

University of Waterloo

BackgroundAdvances in nanotechnology science continue to support developing capabilities to finely tune, control and manipulate the properties of molecules and materials in reduced dimensions (eg. spin, anisotropy, redox potential, light, electrical field, etc) in a manner that enables the creation of new tunable semiconductor electronics including devices utilizing quantum properties.Spintronics is one such example of an emerging technique that takes advantage of electron spin properties to...
Opportunité en vedette

Advanced perovskite films and crystals for stable energy harvesting solar panels

University of Waterloo

BackgroundAdvances in nanotechnology science continue to support developing capabilities to finely tune, control and manipulate the properties of molecules and materials in reduced dimensions (eg. spin, anisotropy, redox potential, light, electrical field, etc) in a manner that enables the creation of new tunable semiconductor electronics including devices utilizing quantum properties.Spintronics is one such example of an emerging technique that takes advantage of electron spin properties to...
Opportunité en vedette

Low-Cost Portable Microfluidic System for Cell Migration Studies

University of Manitoba

Toward providing a full practical solution for performing microfluidic cell migration analysis in an integrated manner, the inventors have developed a prototype USB microscope-based Microfluidic Chemotaxis Analysis System ("UMCAS"). The UMCAS integrates a microfluidic device, gradient and cell imaging, temperature control, and real-time data analysis to provide a low cost and portable solution for rapid microfluidic cell migration and chemotaxis experiments. Furthermore, a smartphone-based...

PEPTIDES A AUTO-ASSEMBLAGE A BASE D'APPARIEMENT D'ACIDES AMINES ET PROCEDES

University of Waterloo

The invention relates to self assembling ß-strand peptides for forming nanostructures, compositions containing the peptides, and methods of forming the peptides. The invention further relates to uses of these peptides in drug delivery and enhancement of drug solubility, biomolecule detection, and biocatalysis applications. The peptides of this invention are further useful in models of protein aggregation disease.

NOUVELLES ENZYMES DE DÉCONSTRUCTION DE LA PAROI CELLULAIRE DE SCYTALIDIUM THERMOPHILUM, MYRIOCOCCUM THERMOPHILUM ET AUREOBASIDIUM PULLULANS, ET LEURS UTILISATIONS

Concordia University

La présente invention concerne de nouveaux polypeptides et de nouvelles enzymes (par exemple des protéines et des enzymes thermostables) ayant des activités relatives au traitement de la biomasse et/ou la dégradation de la biomasse (par exemple la déconstruction de la paroi cellulaire), ainsi que des polynucléotides, des vecteurs, des cellules, des compositions et des outils associés à ceux-ci, ou des variants fonctionnels de ceux-ci. Plus particulièrement, la présente invention concerne des...

NOUVELLES ENZYMES DE DÉCONSTRUCTION DE PAROI CELLULAIRE ISSUES D'AMORPHOTHECA RESINAE, RHIZOMUCOR PUSILLUS ET CALCARISPORIELLA THERMOPHILA ET LEURS UTILISATIONS

Concordia University

La présente invention concerne de nouveaux polypeptides et de nouvelles enzymes (p. ex. des protéines et des enzymes thermostables) ayant des activités associées au traitement et/ou à la dégradation d'une biomasse (p. ex. la déconstruction d'une paroi cellulaire), ainsi que des polynucléotides, des vecteurs, des cellules, des compositions et des outils associés ou leurs variantes fonctionnelles. Plus particulièrement, la présente invention concerne des enzymes sécrétées pouvant être isolées...

UTILISATION DE P27 POUR LA PREVENTION ET LE TRAITEMENT DE L'INSUFFISANCE CARDIAQUE

University Health Network

p27KIP1 (p27) blocks cell proliferation through inhibition of cyclin-dependent kinase 2 (dk2)1. Despite its robust expression in the heart2,3 , little is known about both the function and regulation of p27 in this and other non-proliferative tissues, where the expression of its main target, cyclin E-Cdk2 is known to be very low4. Angiotensin II (Ang II), a major cardiac growth factor5, is demonstrated to induce the proteasomal degradation of p27 through protein kinase CK2-alpha-prime...

SYSTÈMES, PROCÉDÉS ET COMPOSITIONS PERMETTANT DE PRÉDIRE LA MÉTASTASE DANS LE CANCER DE LA VESSIE

GenomeDx Biosciences, Université de la Colombie-Britannique

La présente invention concerne des procédés, des systèmes et des kits de diagnostic, de pronostic et de détermination de l'évolution d'un cancer chez un sujet atteint de cancer. L'invention concerne en outre des procédés et des kits de traitement du cancer chez un sujet. Les méthodes, systèmes et kits impliquent l'analyse de biomarqueurs sur la base de leur expression. L'invention concerne en outre, dans certains cas, des ensembles sonde pouvant être utilisés pour évaluer le stade d'un...

IMPLANTS DE REMPLACEMENT D'OS DOTÉ D'UN MATÉRIAU CELLULAIRE MÉCANIQUEMENT BIOCOMPATIBLE

Université McGill

A methodology integrating multiscale analysis and design optimization to design a novel bone replacement implant made of a functionally graded cellular material that meets fatigue requirements imposed by cyclic loadings. The pore microarchitecture, described by interconnectivity, porosity, pore size as well as pore topology, is optimally designed for tissue regeneration and mechanical strength. The method can contribute to the development of a new generation of bone replacement implants with...

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