Eugenia Kumacheva

Principaux champs de recherche
Chercheur(e)s associé(e)s
Organisations associées

Projets de recherche récents

Advanced Polymer Materials

2012/13-2019/20 • $1,400,000 • PI
Aucun sommaire

Training program in organ-on-a-chip engineering and entrepreneurship (TOeP)

2016/17-2019/20 • $1,050,000 • PI,CO
The long term objective of this training program is to provide a skilled entrepreneurial workforce for Canada, one that will fuel creation of a high-tech economy to replace the shrinking classical manufacturing sector. The statistics are clear: our Universities and research institutions are...

Soft Matter: from Nano to Microscales

2019/20 • $138,000 • PI
This proposal describes a comprehensive research program focused on the fundamental studies of soft matter at nano- and microscales. The unifying theme of three research directions described in the proposal is the structural anisotropy of nanoscale building blocks (metal nanorods, cellulose...

3D bioprinter for fundamental and applied biomaterials research

2019/20 • $105,543 • PI,CO
This application seeks funding for a 3D bioprinter for fundamental and applied research in the field of biomaterials science. It will be used for developing fundamental knowledge about biomaterials' function and performance in vivo. It will be also used for fabricating biomaterials with a broad...

Bioinspired Materials Science

2014/15-2018/19 • $685,000 • PI
To achieve the best energy-, time- and space-efficient performance of biological systems, nature has developed remarkable strategies that rely on self-assembly, structural hierarchy, self-shaping, and synergetic properties of individual structural components. These strategies motivate materials...

A microfluidic platform for personalized throughput drug screening using cancer spheroids

2018/19 • $125,000 • PI
Cancer remains the leading cause of death worldwide. For many patients, standard-of-care therapy involves surgical removal of the primary tumour, however the surgery is often followed by the growth of secondary microtumours at distant locations. Therapies are required that are either toxic...

The development of a nanocolloidal graphene-derived material for water purification and remediation

2018/19 • $25,000 • PI
Zenyatta Ventures Ltd. (Zenyatta) is developing a large deposit of igneous-related high-purity natural graphite.*The higher quality of graphite offers a market advantage over other companies in graphene production. In*order to satisfy market needs and expand the marketability of Zenyatta's...

Advanced composite materials derived from cellulose nanocrystals

2015/16-2017/18 • $444,000 • PI,CO
This proposal exploits cellulose nanocrystals (CNCs), a key Canadian natural resource product and an emerging sustainable, environmentally friendly nanomaterial, in composite materials' manufacturing. The proposed project is of immediate importance to our industrial partners CABOT Corporation...

Properties of Skin-Mimicking Films in Ionic Solutions

2017/18 • $25,000 • PI
Skin cancer is the most prevalent form of cancer, with over 80,000 cases of skin cancer in Canada annually. Sunscreen and sunprotection industry is projected to reach $14.5 billion by 2020. Suncayr, a Canadian company, develops unique preventativemeasures to avoid the common problems associated...

NSERC CREATE Integrated Design of Extracellular Matrices (IDEM)

2011/12-2016/17 • $1,285,000 • PI,CO
The NSERC CREATE program for Integrated Development of Extracellular Matrices (C-IDEM) is a new, multi-disciplinary training program focused on making cell-based therapies a reality. C-IDEM will develop a comprehensive research and training program to help graduate students and other researchers...

Microfluidic studies of carbon dioxide-mediated extraction and phase separation in switchable solvents

2013/14-2015/16 • $427,500 • PI,CO
This proposal exploits a Canadian discovery of the new class of solvents with switchable properties and expertise in developing environmentally benign and cost-, labour- and energy-efficient separation of liquid mixtures. The proposed project is of immediate importance to Switchable Solutions,...

Key Characterization and Synthesis Tools for Defined Polymeric Hydrogels to Guide Cell Fate

2015/16 • $140,618 • PI,CO
The primary objective is to examine the role of the extracellular matrix on cell fate and specifically to design a series of polymeric hydrogels and investigate their impact on cell differentiation, proliferation and guidance. Current methods of growing cells in culture provide limited...

NSERC CREATE Program in Microfluidic Applications and Training in Cardiovascular Health

2010/11-2014/15 • $1,450,000 • PI,CO
Microfluidics has been compared to microelectronics in its potential to influence the way we live our lives. Perhaps the greatest scientific, social, and economic impact of this technological revolution will be its application to the discovery and development of novel therapies to prevent and...

Stem cell counting: Development and application

2012/13-2014/15 • $489,804 • PI,CO
The stem cells of the blood-forming system (hematopoietic stem cells, HSCs) are rare, comprising only 1 in every 20,000 bone marrow cells. Because they are the only cell in marrow with the capacity to sustain blood cell production throughout adult life, they play a central role in many blood...

Optical Device/Material Characterization Facility with sub-100 femtosecond Resolution

2014/15 • $149,800 • PI,CO
The purpose of this grant is to equip a unique user facility within the University of Toronto that enables photonic devices and optical materials research on campus. This research engages at least 50 HQP. More HQP will benefit fro the facility through the collaborative research we carry out with...

Novel CNC-based polarisers to extend the market reach of diode lasers

2014/15 • $25,000 • PI
Laser sources are Laserglow Technologies' main product which requires polarization diversity. Currently, the company manufactures laser sources that emit one (linear) polarization. To expand the marketability of Laserglow Technologies' products, a cost-effective polarization controller needs to...

BiopSys: NSERC Strategic Network for Bioplasmonic Systems

2010/11-2013/14 • $3,483,630 • PI,CO
The aim of the NSERC Strategic Network for Bioplasmonic Systems (BiopSys) is to shorten the time needed for diagnosis and improve prognosis for cancers, such as lung cancer and leukemia, by incorporating plasmonics into diagnostic platforms. Plasmonics is an enabling technology based on an...

Polymers and microfluidics: Discovery and development

2010/11-2013/14 • $544,000 • PI
This proposal describes a research program with two major themes. One of them includes a cluster of materials science projects aimed at the development of new strategies for producing advanced polymer materials. The second theme includes research in the field of microfluidics. Some of the...

Stem cell counting: Development and application

2012/13-2013/14 • $209,496 • PI,CO
The stem cells of the blood-forming system (hematopoietic stem cells, HSCs) are rare, comprising only 1 in every 20,000 bone marrow cells. Because they are the only cell in marrow with the capacity to sustain blood cell production throughout adult life, they play a central role in many blood...

Advanced imaging systems for microfluidic platforms to enable the discovery and development of novel therapeutics

2013/14 • $145,069 • PI,CO
Microfluidic technologies promise to revolutionize discovery and development of new therapeutics for the treatment of a wide range of diseases. To this end, we have established the Centre for Microfluidic Systems (CMS) in Chemistry and Biology at the University of Toronto to provide unparalleled...

A platform for optimization of forumulations of nanoparticle suspensions

2013/14 • $125,000 • PI
This proposal aims at the development of a microfluidic technology platform for efficient screening and optimization of formulations of multicomponent nanoparticle (NP) suspensions. The technology includes high-throughput microfluidic generation of droplets of NP suspensions in monomer or...

Screening of switchable solvents

2013/14 • $25,000 • PI
Sovents that reversibly change their properties under the action of carbon dioxide (switchable solvents) havepromising applications in sustainable Green Chemistry technologies, however currently, the number ofefficient carbon dioxide-binding nitrogenous agents is relatively small, owing to the...

Advanced Polymer Materials

2010/11-2012/13 • $550,000 • PI
Aucun sommaire

Composite materials produced from cellulose nanocrystals and plasmonic nanoparticles

2012/13 • $25,000 • PI
FPInnovations capitalizes on Canada's wood fibre attributes and develops new products and market opportunities within a framework of environmental sustainability. FPInnovations has a scaled-up process to produce pure cellulose nanocrystals (CNCs) in suspension or dried state. These rod-shaped...

Upgrade of energy-loss spectrometer for ultrahigh-resolution TEM

2011/12 • $150,000 • PI,CO
We are requesting an upgrade for the electron energy loss spectrometer installed on the ultrahigh-resolution transmission electron microscope at the Canadian Centre for Electron Microscopy. This upgrade will make it possible to carry out key experiments that cannot be done at the present time:...

Microfluidic reactors for high-throughput screening of chemical formulations

2010/11 • $125,000 • PI
Microfluidics (MFs) has promising applications in high-throughput optimization of formulations for chemical reactions, selection of efficient catalysts, drug discovery, and pharmakinetics. Performing chemical reactions on the microscale, in the continuous mode, and with a rapid change in...

Brevets

PROCEDE DE FABRICATION D'UN POINCON POUR GAUFRAGE A CHAUD

The present invention provides a process for producing a stamp for hot embossing (HE). The stamp can be constructed from any photo-resist epoxy that is stable at temperatures equal to the glass transition temperature (Tg) of the material to be stamped. The stamp can be used repeatedly without significant distortion of features. The stamp benefits from low relative cost, high fidelity of features in all three-dimensions and fast construction. The process for producing a stamp for hot...
Applications connexes: WO2010CA00144, CA20102751057, EP20100738180

DISPOSITIF MICROFLUIDIQUE ET SYSTÈME À ÉLÉMENT DE COUPLAGE OPTIQUE ÉVANESCENT

La présente invention concerne un dispositif microfluidique conçu pour mesurer localement une réflexion totale atténuée à partir d'un canal microfluidique. Le dispositif comprend un substrat dans lequel un canal microfluidique est formé et rendu étanche au moyen d'une couche d'étanchéité collée au substrat. Il comprend en outre une entrée et une sortie fluidiques. Une partie de la couche d'étanchéité est retirée, ce qui expose le canal et forme une ouverture, partie à laquelle est fixée une...
Applications connexes: WO2011CA50176

PLATE-FORME MICROFLUIDIQUE POUR LA PRODUCTION RAPIDE D'ORGANOIDES/SPHEROIDES POUR CRIBLAGE DE COMPOSES

The present disclosure provides a method of producing uniformly sized organoids/multicellular spheroids using a microfluidic device having an array of microwells. The method involves several successive steps. First, a microfluidic device containing parallel rows of microwells that are connected with a supplying channel is filled with a wetting agent. The wetting agent is a liquid that is immiscible in water. For example, the wetting agent may be an organic liquid such as oil. In the next...
Applications connexes: WO2018CA50862, EP20180832771, CA20183069870