Maud Gorbet

Contact via University of Waterloo

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Chercheur(e)s associé(e)s
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Projets de recherche récents

Training in Global Biomedical Technology Research and Innovation

2018/19-2019/20 • $439,800 • PI,CO
Aucun sommaire

Bone-mimetic nanocomposite biomaterials for critically-sized skeletal defect reconstruction

2018/19-2019/20 • $332,776 • PI,CO
Large bone defects occur for many reasons, including bone cancer, failed joint replacments, trauma and even infection. Current approaches to repair these defects use donor bone or large metal implants. Both are poor solutions and they fail often. Some synthetic materials have been developed but...

In vitro model of the closed eye environment and material-induced inflammation

2014/15-2018/19 • $205,000 • PI
Inflammation is an integral part of the cell response to biomedical devices, such as contact lens, stent and vascular graft. Despite many years of research, we have yet to design materials that are able to interact with the human body without causing complications. To design materials that are...

Development of biocompatibility testing and strategy for implantable biosensors

2018/19 • $25,000 • PI
This project is the first collaboration between Gorbet's Material Interactions with Biological Systems lab and*NERv, a startup company, developing an implantable device to monitor post-surgical complications. This*6-month project aims to develop a set of in vitro models allowing NERv to...

Cytation Cell Imaging Multi-Mode Reader

2016/17 • $144,236 • PI,CO
Summary of Proposal for Public Release The University of Waterloo requires a Cytation 5 Cell Imaging and Multi-Mode reader that combines automated digital microscopy with multi-mode microplate bioreader that is able to provide phenotypic cellular information and quantitative measurements of cell...

20/20: NSERC Ophthalmic Materials Network

2010/11-2014/15 • $4,220,600 • PI,CO
Vision, arguably the most critical of the senses, is dependent on healthy ocular tissues. Unfortunately, disease, aging and congenital defects affect the health of these tissues. 20/20: NSERC Network for the Development of Advanced Opthalmic Materials brings together 11 Canadian researchers from...

Upgrade of U of Waterloo's primary confocal microscope with state-of-the-art correlative microscopy for co-applicants in 11 departments

2014/15 • $144,912 • PI,CO
We request purchase of Zeiss "Shuttle and Find" technology which serves as the interface for state-of-the-art correlative microscopy. Zeiss "Shuttle and Find" allows the taking of fluorescent confocal microscope image and then overlay the same ultrastructural image with a Zeiss Merlin electron...

Multiplexed Immunoassay Platform to Quantify Cytokines in Biological Samples

2014/15 • $51,188 • PI,CO
The University of Waterloo requires a high-throughput system for evaluating markers of inflammation ('cytokines') that is able to provide the reproducibility, reliability, robustness, and accuracy required for conducting research on the efficacy and tolerability of new medical device materials...

Development of a rapid and effective in vitro cytotoxicity screening test for ocular biomaterials

2014/15 • $25,000 • PI
Functional contact lenses, such as biosensing or monitoring lenses, are new technologies that are beingdeveloped in industry and the lack of an available cytotoxicity platform limits progress. This new collaborationproject aims to develop a rapid and effective in vitro (lab-based) cell toxicity...

Cell sorter for university facility

2013/14 • $150,000 • PI,CO
A Fluorescence Activated Cell Sorter (FACS) is a machine capable of separating specific individual cells from other cells based on the proteins that they express on their surface. The cell surface proteins used to distinguish these cells are tagged with a fluorescent dye prior to the separation,...

High Resolution Respirometer

2013/14 • $69,903 • PI,CO
Accurately measuring metabolic and mitochondrial function is critical in understanding basic cellular, tissue, and whole body function. To fully understand metabolic and mitochondrial function it is crucial to perform analysis with high sensitive respirometry equipment. Currently, a...

Silicone hydrogel contact lens based delivery system for glaucoma treatment

2010/11-2012/13 • $102,000 • PI,CO
Aucun sommaire

Entry-level confocal microscope needed for 38 users in the Faculties of Science and Engineering at the University of Waterloo

2011/12 • $120,464 • PI,CO
The University of Waterloo desperately requires a second confocal microsope for its multi-user facility. There is only a single, multi-user confocal microscope serving the whole university. This single microscope has logged 10,632 hours of use since it was installed in 2004, and is booked solid...

Cellular mechanisms of material-associated thrombosis

2010/11 • $40,000 • PI
Aucun sommaire

Cellular mechanisms of material-associated thrombosis

2010/11 • $28,020 • PI
While cardiovascular devices have significantly increased the life expectancy of millions of people, their use is not without complications. Despite anticoagulant and anti-platelet therapies, blood clots (thrombus) continue to occur with cardiovascular devices such as stents and heart valves....