Christine Allen

Contact via University of Toronto

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Projets de recherche récents

NSERC CREATE in Polymer Nanoparticles for Drug Delivery (POND)

2017/18-2019/20 • $750,000 • PI,CO
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Cross-linked polyester-based depot systems for sustained drug delivery: determining the relationship between composition, properties and performance

2017/18-2019/20 • $411,627 • PI
There are currently more than 20 pharmaceutical products that include implantable, insertable or injectabledrug delivery systems that are formed from the copolymer poly(lactide-co-glycolide) (PLGA) and providesustained release of drug therapy over time. The sustained drug release that is...

Engineering Block Copolymer and Hybrid Nanotechnologies of Well-Defined Architecture

2016/17-2019/20 • $212,000 • PI
Amphiphilic diblock copolymers that are comprised of individual blocks of hydrophobic and hydrophilic repeat units (e.g. AAAAAABBBBBB) can be synthesized such that they self-assemble, under specific conditions, to form aggregates of well-defined shape and size at the nanoscale. At present, there...

Engineering BioChoice Lignin-Based Microparticles for Applications in Veterinary Medicine

2017/18 • $25,000 • PI
Domtar is the largest integrated producer of uncoated free sheet paper in North America. As a result they are amajor producer of lignin, a relatively low value by-product that is used as a solid fuel to generate process steamand power. Lignin, a substance in the cellular walls of plants, is the...

NSERC CREATE Biointerfaces Training Program

2011/12-2016/17 • $1,300,000 • PI,CO
Our understanding of the nature of the biological/material interface, or biointerface, impacts all materials in biological media from contact lenses to blood contacting materials to diagnostic test strips and new bioseparation media. The CREATE Biointerfaces Training Program will provide unique...

Interactions and molecular organization in polymer surfactant systems

2010/11-2015/16 • $230,000 • PI
Polymer-surfactant pairs play a critical role in many cosmetic and agriculture products as well as paint and pharmaceutical formulations. The high molecular weight polymers and low molecular weight surfactants are often combined to take advantage of their unique and synergistic properties; for...

20/20: NSERC Ophthalmic Materials Network

2010/11-2014/15 • $4,220,600 • PI,CO
Vision, arguably the most critical of the senses, is dependent on healthy ocular tissues. Unfortunately, disease, aging and congenital defects affect the health of these tissues. 20/20: NSERC Network for the Development of Advanced Opthalmic Materials brings together 11 Canadian researchers from...

Development of abuse-deterrent nanotechnology formulation for effective pain management

2014/15 • $25,000 • PI
Altus Formulation Inc. is focused on the development of drug delivery technologies to generate cost effective 'safe to use' products to improve the lives of patients. Altus has developed an innovative series of amphiphilic and pH-sensitive block copolymers that can self-assemble in aqueous media...

Gold Nanotechnology for Delivery of OCZ103

2012/13 • $25,000 • PI
Oncozyme Pharma Inc. is uniquely focused on the treatment of cancer via development of drugs that target DNA repair enzymes such as endo-exonucleases. Studies conducted by Oncozyme have identified a series of potent inhibitors (OCZ compounds) of a key endo-exonuclease enzyme resulting in...



Devices, materials, compounds, systems, and processes for Cherenkov-Activated Nuclear-Targeted Photodynamic Therapy that involves generating Cherenkov light within the tissue of a target volume and using this light to activate photosensitizing material that is located in the nucleus of cells of the target volume.
Applications connexes: EP20170798468, WO2017CA50614, CA20173064112