Alan Fine


Contact via Dalhousie University


Principaux champs de recherche
Chercheur(e)s associé(e)s
Organisations associées

Projets de recherche récents

Engineering biosensors for fluorescence imaging of neuronal signalling in whole animals

2012/13-2017/18 • $676,462 • PI,CO
Proteins are the tools that orchestrate and perform the countless biochemical reactions required for thought, growth, and proliferation. Proteins are also one of the most important classes of tools used for the study of these very same biochemical processes. For example, fluorescent proteins...

Lensless microscopy for rapid portable hematology diagnostics at the point of care

2015/16-2017/18 • $431,955 • PI,CO,Other
We are developing a new lensless imaging technology for point-of-care diagnostic testing. This technology enables us to create pocket-sized diagnostic devices with greater resolution but far lower cost than ordinary lens-based microscopes or other instruments for corresponding diagnostic use....

Lensless microscopy for rapid portable hematology diagnostics at the point of care

2015/16-2016/17 • $431,955 • PI,CO
We are developing a new lensless imaging technology for pointof-care diagnostic testing. This technology enables us tocreate pocket-sized diagnostic devices with greater resolution but far lower cost than ordinary lens-based microscopes orother instruments for corresponding diagnostic use. These...

NSERC CREATE Training Program in Biophotonics

2010/11-2015/16 • $1,646,225 • PI,CO
The future of progress in Life Sciences, from understanding basic biochemistry to complex biological organisms and environmental issues, hinges critically on our ability to improve our ways to study and manipulate molecules and living organisms with increased precision and reduced invasiveness....

Learning in zebrafish

2010/11-2014/15 • $135,000 • PI
My proposed research program is aimed at clarifying the capacity, development, and structural underpinnings of olfactory learning in zebrafish. The small size, relative transparency, and genetic tractability of these animals have made zebrafish widely used models for study of vertebrate...

Effects of experience on the early development of the olfactory system

2014/15 • $100,000 • PI,CO
Olfactory cues play essential roles in psychosocial development. For instance, mother-infant bonding and mate selection are shaped by early olfactory experience; studies also show olfactory deficits associated with a large range of disorders such as autism, depression, anxiety, schizophrenia,...

Mechanisms of long-term plasticity expression in the forebrain

2010/11-2012/13 • $442,461 • PI
Understanding the biological basis of learning and memory is a major challenge of neuroscience, with medical ramifications of great potential importance. Abundant evidence suggests that memories are stored as sets of changes in the strength of synaptic connections between neurons in the brain....

CIHR Team in Memory

2010/11 • $825,417 • PI,CO
Learning and memory impairments are important aspects of some of the most common and debilitating neurological disorders, including Alzheimer's disease, schizophrenia, and Parkinson's disease, and are frequent concomitants to "normal" aging. The processes of memory and learning appear to involve...

States of Mind: Emerging Issues in Neuroethics

2010/11 • $275,300 • PI,CO
In 2001, at the close of the decade designated by presidential proclamation as the ¿Decade of the Brain¿, William Safire coined the phrase ¿neuroethics¿ and, from the platform of his column in the New York Times, announced the need for such a discipline. The proposed States of Mind New Emerging...

Contact Optical Microscopy

2010/11 • $148,684 • PI,CO
We propose to develop and commercialize a family of new devices for contact optical microscopy. This invention represents a simple, powerful and widely applicable technology that can cheaply and easily achieve resolution beyond the classical diffraction limits of conventional microscopy. This is...

MagA as a MRI Reporter Gene Related to Learning and Memory

2010/11 • $17,500 • Scholarship/Fellowship,Other
The goal of this project is to develop new techniques in magnetic resonance imaging (MRI) and to apply those techniques to study learning and memory. A reporter gene (in this case magA) is basically a gene that can be used to generate contrast in MRI. This contrast is necessary because it...

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