John J. Cox


Contact via McGill University


Principaux champs de recherche
Chercheur(e)s associé(e)s
Organisations associées

Projets de recherche récents

Tracking a revolution: Evaluating the impact of modern HCV therapy on HIV-HCV coinfection

2015/16-2020/21 • $4,320,989 • PI,Other
RESEARCH PROGRAMNew, highly effective therapies that directly target HCV (DAAs) will completely alter the landscape for HCV infected patients. But we are faced with a fundamental paradox. DAAs are the most expensive anti-infectives ever to be developed and HCV disproportionately affects the...

CRISM-Quebec-Maritimes: Research on interventions in drug misuse

2014/15-2020/21 • $2,374,845 • PI,CO,Other
Substance misuse remains a significant global public health problem which carries a heavy burden for abusers and their families alike. This disorder is indeed associated with suffering and severe health problems in patients, distress among family members, as well as tremendous costs to society....

Antiretroviral-based HIV prevention and its impact on sexual risk behaviours and HIV/STIs among gay, bisexual and other men who have sex with men: Engage Cohort Study

2019/20-2020/21 • $1,406,554 • PI,CO
In Canada, half of new HIV cases continue to be among gay, bisexual, and other men who have sex with men (gbMSM). GbMSM are also more affected by sexually transmitted infections (STIs) such as syphilis. Antiretroviral (ARV)-based HIV prevention, such as Treatment as Prevention (TasP; screening,...

Vaccination & screening for control sexually transmitted infections (STIs) and STI-related cancers

2016/17-2020/21 • $1,028,050 • PI,Other
Sexually transmitted infections (STI) are a major public health concern among Canadians. Human papillomavirus (HPV) is the most common STI, so much so that ¾ people will get this infection at least once. This is concerning because certain HPV types cause cervical, anal, and oral cancers. Rates...

Engage-COVID-19: A mixed methods study of biomedical, behavioural, and psychosocial aspects of the COVID-19 pandemic among gay, bisexual, and other men who have sex with men in Canada

2020/21 • $687,901 • PI,CO,Other
Gay, bisexual, and other men who have sex with men (GBM) have historically experienced significant disparities in physical, mental, and sexual health, amplified by systemic marginalization and high barriers to healthcare. This context of inequity creates heightened vulnerabilities to COVID-19....

Mentoring new patient-oriented researchers in innovative HIV e-care

2016/17-2020/21 • $381,898 • PI,CO,Other
HIV medications are getting better but for many HIV-infected Canadians taking their lifelong medication is a serious challenge. Current HIV care insufficiently addresses this. Better consideration of the patient's perspective during medical visits could help. Dr. Lebouche's research program...

Model-based impact evaluation of pre-exposure prophylaxis on HIV transmission among men who have sex with men in Montréal

2018/19-2020/21 • $323,627 • PI,CO
Over the last decade, the number of HIV diagnoses among men who have sex with men (MSM) has failed to decline in Quebec despite the public health response. Pre-exposure prophylaxis (PrEP) - taking a daily antiretroviral pill - can prevent HIV acquisition among those who do not have HIV but are...

Towards the micro-elimination of hepatitis C virus among Canadian provincial prison inmates: The effectiveness of patient navigation on treatment uptake

2019/20-2020/21 • $162,990 • PI,CO
The prevalence of chronic hepatitis C virus (HCV) infection is approximately 40-fold higher among provincial prison inmates compared to the Canadian population. Left untreated, there is ongoing risk of transmission within prisons and to the community at large upon release. Treatment of prisoners...

A randomized trial of doxycycline chemoprophylaxis for the prevention of sexually transmitted infections in gay, bisexual and other men who have sex with men (gbMSM)

2020/21 • $153,000 • PI,CO
Globally, syphilis, chlamydia and gonorrhea are three of the most common sexually transmitted infections (STI). Over the last decade, these STIs have seen a resurgence in many parts of the world, including Canada, with the bulk of infections seen in major urban centres. More recently, these...

Effectiveness of human papillomavirus vaccine in gay, bisexual and other men who have sex with men

2020/21 • $142,481 • PI,CO
Public health experts recommend human papillomavirus (HPV) vaccine for males and females. In some Canadian provinces, there is a publicly funded HPV vaccine program for young men up to 26 years old who are gay or bisexual or are other men who have sex with men. These men are at higher risk for...

COVID-19 Variant Supplement - Engage-COVID-19: A mixed methods study of biomedical, behavioural, and psychosocial aspects of the COVID-19 pandemic among gay, bisexual, and other men who have sex with men in Canada

2020/21 • $50,000 • PI,CO,Other
Gay, bisexual, and other men who have sex with men (GBM) have historically experienced significant disparities in physical, mental, and sexual health, amplified by systemic marginalization and high barriers to healthcare. This context of inequity creates heightened vulnerabilities to COVID-19....

HIV Prevention for Gay and Bisexual Men: A Multisite Study and Development of New HIV Prevention Interventions

2014/15-2019/20 • $500,000 • PI,CO,Other
Despite important advances in antiretroviral therapy (ART) that have resulted in improvements in health for HIV-infected individuals and successes in HIV prevention work in the late 1990s, half of HIV new cases continue to be among gay, bisexual, and other men who have sex with men (gbMSM) in...

Engage Cohort Study Meeting: National Knowledge Translation Planning Event

2019/20 • $20,000 • PI,CO,Other
Since the start of the HIV epidemic, gay, bisexual, and other men who have sex with men (GBM) have carried the highest burden of HIV infection in Western countries, including Canada. Despite major developments in HIV therapies and ongoing prevention work, this remains true today. More than half...

Engage Meeting: National Knowledge Translation and Cohort Study Planning Event

2019/20 • $17,257 • PI,CO,Other
Since the start of the HIV epidemic, gay, bisexual, and other men who have sex with men (GBM) have carried the highest burden of HIV infection in Western countries, including Canada. Despite major developments in HIV therapies and ongoing prevention work, this remains true today. More than half...

Optimizing the impact of internet-based testing for the control of HIV and sexually transmitted infections among gay, bisexual, and other men who have sex with men

2014/15-2017/18 • $372,583 • PI,CO,Other
The internet has changed the nature of gay communities and how knowledge is accessed. The majority of men who have sex with men (MSM) use the internet to meet sexual partners, and most also use it to look for health information. BCCDC has developed an internet-based service for testing for HIV...

How is biomedical HIV prevention changing risk behaviour among gay and bisexual men? A multisite cohort study.

2017/18 • $100,000 • PI,CO
Half of new HIV cases continue to be among gay, bisexual, and other men who have sex with men (MSM) in Canada, and MSM are also disproportionately burdened by other sexually transmitted infections (STIs), such as syphilis and Hepatitis C Virus. Simultaneously, new medications used to prevent HIV...

L'accès aux soins et aux traitements antirétroviraux pour les personnes vivant avec le VIH sans considérer le statut d'immigration : Vers une couverture sanitaire universelle au Québec

2017/18 • $38,978 • PI,CO,Other
Au Quebec, des personnes vivant avec le VIH (PVVIH) eprouvent encore des difficultes complexes d'acces aux soins de sante et aux traitements antiretroviraux (TAR) a cause de leur statut d'immigration ou de l'absence de celui-ci. Pourtant les PVVIH sans recours aux TAR ont un risque tres eleve de...

A Two-eyed seeing approach to wholistic healing and wellness for people with drug-use experience

2016/17 • $148,960 • PI,CO,Other
The TRC squarely positioned the erosion of Indigenous Ways of Being and Ways of Knowing, as well as our societies, institutions and economies as the intended result of Canada's colonization. Residential schools, the 60s scoop and more recently, the hugely disproportionate number of Indigenous...

Impact of HIV on aging-related comorbidities among key affected populations across Canada

2014/15-2015/16 • $187,500 • PI,CO,Other
HIV-positive individuals may have higher risk of aging-related comorbidities, such as liver, renal, and cardiovascular diseases and cancers, compared to the general population. However, to date no study has comprehensively examined the burden and impacts of aging-related comorbidities among...

Stemming the epidemic of liver related morbidity and mortality in HIV-HCV co-infection: Is ART enough?

2010/11-2014/15 • $1,924,155 • PI,CO
An increasing number of people are infected with both Hepatitis C (HCV) and HIV. HIV appears to make HCV related liver disease progress more rapidly. Liver disease is now one of the leading causes of illness and death in HIV-HCV-infected persons. By restoring the immune system, it was expected...

Subvention de formation des IRSC-FRSQ en recherche transdisciplinaire sur les interventions en santé publique: promotion, prévention et politiques publiques (4P)

2010/11-2014/15 • $1,665,921 • PI,CO
La complexite des problemes auxquels les autorites de sante publique (SP) et les autorites responsables des politiques et de l'organisation des services sociaux et de sante (POSSS) au Canada seront confrontes requiere une amelioration de la capacite de recherche transdisciplinaire et du partage...

Prospective investigation of the relationship between food insecurity and health and behavioural outcomes in HIV-HCV co-infection: clues for prevention interventions

2011/12-2014/15 • $449,650 • PI,CO
HIV infection has become a chronic manageable condition in Canada where combined antiretroviral treatments are available. This change has led to an increase in the occurrence of various competing morbidities among HIV-infected populations. This is especially true for hepatitis C virus (HCV)...

The Coming Revolution in HCV Therapy: Will HIV-HCV co-infected patients really benefit?

2014/15 • $100,000 • PI,CO
HIV- Hepatitis C (HCV) co-infection is a growing concern across Canada. Evidence suggests that co-infected individuals advance faster to endstage liver disease (ESLD) compared to HCV mono-infected patients. Effective combination antiretroviral therapy has lead to a significant decline in deaths...

CRISM-QUÉBEC: Réseau Québécois -Recherche sur les interventions en abus de substances/Research on Interventions for substance misuse

2013/14 • $49,832 • PI,CO,Other
Substance misuse remains a significant global public health problem which carries a heavy burden for abusers and their families alike. This disorder is associated with suffering and severe health problems in patients, distress among family members, as well as tremendous costs to society....

HIV Prevention for Gay and Bisexual Men: A Multisite Cohort and Development of New HIV Prevention Interventions

2013/14 • $10,000 • PI,CO,Other
Half of new human immunodeficiency virus (HIV) infections in Canada occur among gay, bisexual, and other men who have sex with men (MSM). Over the past ten years, there have been important developments in HIV treatment and prevention. For example, the use of antiretroviral medication therapies...

Analyse de l'implantation d'une intervention communautaire de dépistage rapide du VIH offerte aux hommes ayant des relations sexuelles avec d'autres hommes dans la région de Montréal

2010/11-2011/12 • $200,000 • PI,CO
Des donnees recentes indiquent que parmi les hommes ayant des relations sexuelles avec des hommes (HARSAH) qui sont seropositifs au VIH, un nombre important ignore leur statut serologique. L'ignorance de ce statut revele que des HARSAH sont peu ou pas rejoints par l'offre de depistage actuelle....

Expanding HIV care models to meet the challenge of multi-morbidities in vulnerable populations

2011/12 • $25,000 • PI,CO
Tremendous advances have made in the treatment of HIV/AIDS rendering it a manageable chronic condition. As HIV-infected persons now survive for decades after acquiring their infection, co-morbid conditions increasingly impact health care access, clinical outcomes and costs. Important...

Pro-Active Intervention to Limit HIV Transmission among MSM Populations

2010/11 • $145,308 • PI,CO
This project brings together a team of the Reseau SIDA of the FRSQ to work together in the area of HIV prevention in regard to men who have sex with men (MSM). Our project is based on the competence of virologists, public health officials, social scientists, clinicians, and community workers and...

Evaluation of "Action To Moblize Change" (ATOMC), a social network intervention for increasing HIV testing among MSM at high-risk for infection in Montreal.

2010/11 • $33,000 • PI,CO,Other
A social network HIV testing pilot project for MSM (Action TO Mobilize Change, ATOMC) was recently funded by the Public Health Department of the Health and Social Services Agency of Montreal. The pilot project is based on work done by the Centers for Disease Control and Prevention using social...

Evaluation d'un programme d'interventions sur mesure "tailored" visant à optimiser l'adhésion à la prise des antirétroviraux auprès de personnes vivant avec le VIH

2010/11 • $15,893 • PI,CO
A l'heure actuelle sans pouvoir eradiquer le VIH, les therapies virales existantes permettent, par la suppression de la replication virale, de maintenir et d'ameliorer la fonction immunitaire des personnes infectees. Cependant, l'arret, meme temporaire, des therapies permet au virus de se...

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