Generating innovation through the use of common data: Improving the diagnosis and treatment of pediatric and adolescent mild traumatic brain injury in Canada.

Renseignements sur le financement
Canadian Institutes of Health Research
  • Type de subvention: Subvention d'équipe : les traumatismes craniocérébraux légers chez les enfants et les adolescents - Fonds de recherche du Québec - Santé
  • Années: 2012/13 à 2017/18
  • Financement total: $766,895
Mots clés
Chercheur(e) principal(e)
Collaborateur(s)
Partenaires

Sommaire du projet

The incidence of pediatric traumatic brain injury (TBI) in North America is alarmingly high; studies suggest that mild TBI (mTBI) make up 70-80% of all cases reported. Of particular concern is that not only do many post-concussive symptoms, which manifest as cognitive, physical and behavioural deficits, persist for a subset of patients, but there is very little consensus among clinicians and researchers on how to diagnose and treat mTBI. Furthermore, there is a dearth of research examining the long-lasting effects of sustaining multiple mTBIs. One factor that contributes to this lack of consensus is that many clinicians and researchers use different tools or methods to collect data, thus making comparisons across sites challenging. Given this, we have assembled a team of nationally and internationally distinguished clinician scientists, researchers, and knowledge users from across Canada, whose innovative research programs and clinical initiatives have had a significant impact on the field of pediatric mTBI. We propose to create a comprehensive, flexible and sustainable data management system that will serve to significantly advance clinical care via amalgamated and accessible research evidence. The goal of this mTBI Team Grant is to create a culture of national collaboration, data collection and rapid clinical uptake of innovation in discovery. Our overall goal is to enhance our ability to conduct multi-centre research and provide evidence-based care across Canada that will assist in diagnoses and treatment of pediatric mTBI.

Recherche connexe

Each year, millions of children sustain concussions/mild traumatic brain injuries (mTBI), and 15-25% suffer persistent symptoms and declines in quality of life. Clinicians caring for these children face three critical, unanswered questions: how to di... Plus ...
Challenge Current therapies are ineffective in many aggressive cancers, which are often refractory to therapeutic interventions and develop drug resistance. Combination therapies could effectively address this issue, however, to select the right comb... Plus ...
People living with HIV are worrying about their memory, and with good reason. Even with good control of the infection, up to 50% may have cognitive or depressive symptoms. These changes in thinking and mood are usually mild, but they seem to matter i... Plus ...