Bridging the Gap in Paediatric Traumatic Brain Injury: Environmental, biological and clinical markers associated with preschool concussion and TBI

Renseignements sur le financement
Canadian Institutes of Health Research
  • Type de subvention: Subvention Fondation
  • Années: 2016/17 à 2020/21
  • Financement total: $981,156
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Sommaire du projet

Concussions and other traumatic brain injuries are a frequent cause of death and disability in youth, and children under the age of 6 are at particularly high risk. Older children with brain injuries often suffer serious mental, psychological, social, and behaviour problems. Even mild injuries have the potential to cause lasting problems in children because of subtle changes in how the brain works. Recently, international teams have been working to better understand the course of recovery in children with concussion or brain injury; however, children under 6 have generally been excluded from this research. This is extremely problematic because of the high prevalence of brain injuries in toddlers and preschoolers and because they are particularly vulnerable to the effects of brain injury. Indeed, injury to the brain disrupts normal development and critically affects acquisition of new knowledge and skills. Currently, we know very little about the consequence of brain injuries in young children, or what initial signs and symptoms might help us predict development in later years. This research program will investigate the functioning of young children after they sustain brain injuries and determine how we can predict their outcomes. We will also determine whether functional problems are associated with changes in the integrity of the brain or particular genetic predispositions. The results will help us to better understand how problems develop after brain injuries in the youngest and most vulnerable age group. In turn, these findings will lead to the development of clear guidelines for doctors and health practitioners to follow when treating young children after a concussion or brain injury. We will also be able to quickly identify preschoolers who are at-risk for problems after brain injury and provide them and their families with the resources needed to prevent problems before they occur and to foster their development and quality of life.

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