New Brunswick Health Research Foundation

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Projets de recherche récents

Phase Two of the Canadian Consortium on Neurodegeneration in Aging

2019/20-2020/21 • $12,909,697
The Canadian Consortium for Neurodegeneration and Aging (CCNA) is an important response to the urgent health problem of Alzheimer Disease (AD) and other more rare dementias-together termed the neurodegenerative diseases (NDD)- in Canada. Our mission is to create teams and platforms that will do...

Maritimes SPOR Support Unit

2013/14-2020/21 • $12,450,911
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Case management in primary care for frequent users of healthcare services with chronic diseases and complex care needs: implementation and realist evaluations

2017/18-2020/21 • $838,575
A common reason for frequent use of health care services is the complex health care needs of individuals suffering from multiple chronic conditions, often together with mental health comorbidities and/or social vulnerability. Individuals with such complex health care needs require a variety of...

CIHR SPOR Mentorship Chair in Innovative Cancer Clinical Trials

2016/17-2020/21 • $443,763
Training Young Scientists in Patient-Oriented Research in Cancer Treatment and Care Cancer is one of the most common and toughest health problems for Canada. Key to fighting cancer are the research studies that try to find new and improved treatments for the disease, so that health care...

Implementing Mental Health Recovery Guidelines Into Services: A Pan Canadian Study

2017/18-2020/21 • $413,906
Implementing Mental Health Recovery Guidelines Into Services: A Pan-Canadian Study (Piat, Briand, Mantler Albert, Doiron, Maillet, et al)Issue to be addressed: The aim of this project is to facilitate system transformation to a mental health recovery perspective by implementing and evaluating...

Indigenous Research Chair in Nursing, New Brunswick

2019/20-2020/21 • $215,450
The Indigenous Research Chair in Nursing provides an exceptional opportunity to contribute leadership in advancing Indigenous peoples' health and Indigenous nursing in New Brunswick and Atlantic Canada. The Chair will develop and implement a community-engaged research program focused on health...

Traumatic stress and Mental Health Impacts of the COVID-19 Pandemic on Front-Line Workers in Homeless Services

2020/21 • $187,556
Lay Abstract: This proposal addresses the mental health impacts of the COVID-19 pandemic on frontline workers in the homeless sector. Prior to the COVID-19 pandemic outbreak, our research reported high levels of direct traumatic stress among frontline workers. In five previous studies, we...

Substance use disorder treatment transformations due to the COVID-19 pandemic: Impact on Indigenous patients and communities

2020/21 • $157,124
The COVID-19 pandemic has had a serious impact on Indigenous Peoples across Canada. One area of concern pertains to the disruption of substance use treatment and recovery. Indigenous Nations have rapidly transformed services to expand access through telemedicine and greater access to...

Development, implementation, and evaluation of equitable and effective e-mental health care delivery for parents and care givers struggling with anxiety and depression arising during the COVID-19 pandemic: improving access and matching services to need.

2020/21 • $144,696
Parents, particularly women, are experiencing heightened anxiety and depression during the COVID-19 pandemic. It is unclear which specific stressors faced by parents are overwhelming their coping resources during COVID-19. Evidently though, treatment is needed. E-mental health care has become a...

Implementing & Scaling Up the LTC Palliative Toolkit During COVID

2020/21 • $107,498
The impact of the COVID-19 pandemic on the Canadian long-term care (LTC) sector has been a national tragedy. Similar to many other countries, Canada has observed an unprecedented and exponential increase in the number of deaths in LTC due to the COVID-19 pandemic. Prior to COVID-19, our...

Canadian Consortium on Neurodegeneration in Aging - Full Proposal

2014/15-2018/19 • $24,450,000
The neurodegenerative brain diseases - Alzheimer's Disease, Vascular dementia, Frontotemporal dementia, and Dementia with Lewy Bodies - will be the "diseases of the 21st century" due to aging of our population. The decision by CIHR to establish a Canadian Consortium on Neurodegeneration in Aging...

Interventions to Support Transitions in Care for Children and Families with Complex Health Care Needs in the Community

2018/19 • $25,000
Children and youth with complex health care needs have a variety of conditions that range from less severe to life-threatening or life-limiting. For example, some children depend on medical devices and technologies whereas others require less intensive supports to live, work, and play in...

Maternal prenatal negative mood & infant stress and immunity: Could increased maternal inflammation during pregnancy be the linking mechanism?

2011/12-2016/17 • $150,000
Pregnancy is a process of change requiring adaptation. Maternal negative prenatal feelings can interact with this adaptation. Negative feelings, such as depressed and anxious states, may influence the course of a pregnancy. However, there is still very little research on how negative feelings...

Mapping the Pax-5 cancerous interactome in breast cancer cells

2010/11-2015/16 • $150,000
Breast cancer is the most common female malignancy worldwide. In Canada, 1 in 8 women are predisposed to develop breast cancer where 33% of these women will succumb to their disease. Thus, the identification of genes involved in the development of cancer (oncogenesis) is essential for a...

Understanding the cytoplasmic roles of hnRNP A1

2010/11-2015/16 • $150,000
Genetic information flows from DNA to RNA to protein, and this information flow is regulated at several points. How the information encoded by RNA is regulated depends on proteins that bind to the RNA, which affect how the RNA is used to make new proteins. Importantly, the flow of information...

Intervention models for preschoolers with autistic spectrum disorder (ASD): A population-based comparative effectiveness study

2012/13-2014/15 • $399,417
More and more Canadian children are being diagnosed with autistic spectrum disorders (ASD). These disorders lead to significant differences in children's ability to interact, communicate, and play like other children, and can have a devastating impact on families. Canadian provinces have...

Exploring the Educational Imperatives to Support Successful Electronic Health Record Integration

2011/12-2014/15 • $78,958
Health information technology (HIT) is a term used to describe the collection and management of information in a variety of healthcare environments. There is a rise in the use of HIT within health care settings. An electronic health record (EHR) is one example of a HIT that is being introduced...

Le contrôle de la distribution des acides gras polyinsaturés dans les glycérophospholipides membranaires.

2011/12-2014/15 • $41,060
Les phospholipides sont les constituants lipidiques majeurs des membranes cellulaires et ils contiennent deux molecules d'acides gras. Par contre, il existe une tres grande diversite d'acides gras et de classes de phospholipides. Certains acides gras polyinsatures, comme l'acide arachidonique...

L'activité transcriptionnelle des différents variants du promoteur de la 5-lipoxygénase

2011/12-2014/15 • $41,060
La 5-lipoxygenase (5-LO) est une proteine/enzyme exprimee principalement par les globules blancs. Elle est essentielle pour la production de leucotrienes, des lipides bioactifs associes a plusieurs maladies inflammatoires telles que l'asthme et l'atherosclerose. Cette association entre la 5-LO...

An Interprofessional Approach to Improving the Health of Obese Adults in New Brunswick.

2011/12-2013/14 • $217,694
This intervention study is a joint venture between a provincial health authority, university researchers and community groups in New Brunswick aimed at creating a physician referral destination program for obese patients seeking to improve their health through behavioural change, nutritional...

Understanding the cytoplasmic roles of hnRNP A1

2010/11-2013/14 • $142,485
Genetic information flows from DNA to RNA to protein, and this information flow is regulated at several points. How the information encoded by RNA is regulated depends on proteins that bind to the RNA, which affect how the RNA is used to make new proteins. Importantly, the flow of information...

Unraveling the complex web of resident transitions through gender analysis and methodological exploration

2010/11-2013/14 • $82,500
There are a number of problems that are known to occur when residents of long-term care (LTC) facilities transfer to a hospital Emergency Department (ED) and later return to LTC. Assumptions about roles and miscommunicaton between staff of both care settings regularly occur and result in medical...

New Brunswick SPOR Primary and Integrated Care Innovations

2013/14 • $75,000
As part of the SPOR Network, we envision to develop, evaluate and scale up existing and new integrated primary health care models using a variety of approaches with a specific focus on patients with complex needs. Embedded in the models will be an examination and management of patient and health...

Neuro-biomechanical factors in the design of transfemoral knee prostheses

2011/12-2013/14 • $74,168
Although the ability to walk safely and efficiently is greatly reduced for a lower-extremity amputee, powered (micro-controlled) knee prostheses are now commercially available and have shown dramatic improvements in walking ability of amputees who use them. However, while technically advanced,...

Men's health promotion and workforce engagement in the context of workplace bullying

2010/11-2013/14 • $65,994
Canada has one of the highest rates of workplace bullying in the world. Workplace bullying has negative social, health, and economic outcomes. Little is known about how workplace bullying affects men's capacity to look after their health or continue in the workforce. Employed men are essential...

Concealment to Engagement: Helping Women Overcome Secrecy and Isolation Associated with Eating Disorders

2011/12-2013/14 • $35,000
Women with eating disorders (ED) may experience feelings of shame and embarrassment, often choosing to keep their condition secretive, remain socially isolated and avoid treatment. Without support, women may experience negative health outcomes (e.g. cardiovascular, dental, reproductive, and...

Evaluation of RNAO Best Practice Guideline for Healthy Work Environments in a Nursing Home Setting

2010/11-2013/14 • $33,000
The population of elderly people in Canada is growing at an unprecedented rate. Many elderly people will require long term care services that are provided by nursing homes. It is vitally important that nursing homes have sufficient numbers of qualified staff to provide the required care and...

An Exploratory Study of the Feasibility and Efficacy of a Primary Health Care Intervention for Women in the Early Years After Leaving an Abusive Partner

2010/11-2012/13 • $344,444
The purpose of this study is to evaluate an outreach health intervention delivered by nurses and linked to existing community services for women who have recently left abusive partners in New Brunswick. In Canada, 1 in 3 women experiences abuse from a male partner. Women who experience abuse...

Sustainable Telephone-Based Peer Support for Mothers with Postpartum Depression

2010/11-2012/13 • $340,995
Postpartum depression (PPD) is the most frequent illness experienced by new mothers. Nearly 1 in 7 mothers experience PPD, characterized by symptoms such as low mood, loss of energy, agitation, insomnia or tiredness, excessive guilt, confusion, and thoughts of self harm. Nearly 50% of women with...

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