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In Vitro gastrointestinal model system

Laval University

Description Fresh faecal samples are used as the source of inocula for immobilization in a mixed gel of gellan and xanthan. The beads produced are then introduced in a single or multi-stage chemostat fed with a nutrient media. The composition and metabolic activities of the flora are monitored daily in reactors operated with conditions simulating the characteristics of different segment of the gastrointestinal tract. It consists in an environment more akin to that of the gastrointestinal...
Featured Opportunity

IG Fitting

University Health Network

Method for T1 Mapping with Incomplete Tissue Magnetization Quantitative T1 mapping has shown promise for early identification and discrimination of pathology in a wide range of cardiac diseases. The conventional Modified Look-Locker Inversion Recovery (MOLLI) technique of T1 mapping requires rest periods to allow magnetization to fully recover to its equilibrium value at the end of each inversion grouping. Unfortunately, these rest periods can significantly reduce the efficiency and/or...

METHODS AND APPARATUS FOR CRYSTALLIZATION OF SALTS

University of Saskatchewan

Method or apparatus for increasing the production rate, size, and/or quality of salt crystals produced from salt containing solutions by controlling temperature, evaporation, and/or circulation of the salt-containing solution. The salt-containing solution may be a salt-containing solution in a crystallization pond obtained as a product of solution mining, such as a KCl-containing solution obtained as a product of solution mining of a potash mine. Apparatuses may be provided to actively cool...

ADAPTIVE CONTROL TECHNIQUE FOR TRANSMISSION LINE CONTROL DEVICES TO HANDLE LARGE DISTURBANCE SCENARIOS

University of Saskatchewan

Various embodiments are described herein for a device and method for an adaptive controller for a power system. The adaptive controller has a parameter identification module and an adaptive control module. The parameter identification module determines values for parameters of a power system model based on a constrained parameter identification technique, errors between actual and estimated power system outputs and a control signal. The adaptive control module applies an adaptive pole-shift...

SYSTEMS AND METHODS OF ENHANCING ELECTRICAL ACTIVATION OF NERVOUS TISSUE

University of Toronto

Methods and systems for improving nerve stimulation are disclosed and are termed enhanced transcutaneous electrical stimulation (eTENS). One embodiment can be used for enhancing the excitation properties of neural tissue. In one embodiment, systems and methods are provided to enable the selective modulation of specific (targeted) neural substrate, while minimizing the activation of adjacent (non-targeted) nervous tissue, or differentially providing different modulation signals to tissue...

High frequency ultrasound imaging using contrast agents

Sunnybrook Health Sciences Centre

A method for producing an ultrasound image comprising administering contrast agent to a laboratory animal; generating ultrasound at a frequency of at least 20 MHz; transmitting ultrasound at a frequency of at least 20 MHz into the subject; receiving non-linear ultrasound from the contrast agent in the subject; and processing the received ultrasound to provide an image.

APPARATUS AND METHOD FOR OUT-OF-STEP PROTECTION USING STATE PLANE TRAJECTORIES ANALYSIS

University of Saskatchewan

Various embodiments are described herein for a device and method for predicting an out-of-step condition in a power system due to a disturbance, such as a fault, where the power system comprises a power generator. The method comprises determining values for a state plane trajectory for the power generator during the disturbance based on using an internal voltage angle of the power generator and a during fault rotor speed of the power generator as state variables, determining time scale...

PH-SENSING MICROENCAPSULATION SYSTEM

University of Alberta

Smart pH-sensing microencapsulation system programmed to actively respond to environmental pH change has long been considered a key technology in pharmaceutical industries and food sciences. Maintenance of both stability of active materials in harsh gastrointestinal (GI) tract environments and release at target site-specific pH is a major obstacle in oral drug/vaccine development. In this study, we developed a first-of-its-kind drug delivery system with pH-responsive macropores. Opening and...

BONE REPLACEMENT IMPLANTS WITH MECHANICALLY BIOCOMPATIBLE CELLULAR MATERIAL

McGill University

An implant for bone replacement comprises a graded cellular body having a non-homogeneous distribution of material properties. The graded cellular body is defined by a plurality of unit cells, each of said unit cells having a lattice microstructure and a cell topology, either closed or open, and a pore geometry. The pore geometry is defined by pore size, pore shape and wall thickness. The pore size of the unit cells at implant boundaries is in the range between 50 micron and 800 micron to...

WEARABLE RESPIRATION SENSOR AND RESPIRATION MONITORING SYSTEM

Laval University

There is described a wearable respiration sensor generally having a stretchable textile substrate to be worn around a user's torso; and a dipole antenna having two flexible conductive elements extending in opposite directions from a center, relative to a dipole axis, and being secured to the stretchable textile substrate, each of the two flexible conductive elements having a proximate end near the center, a distal end away from the center, and a curved portion curving away from and back...

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