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Diagnosing Cognitive Impairment After COVID-19 Infection

Queen's University

Eye-tracking as a non-invasive tool capable of identifying COVID-19 patients at risk for neurological impairments

SYSTEMS AND METHODS FOR COGNITIVE HEALTH ASSESSMENT

McMaster University

An improved system for assessing cognitive function is described that uses tracked electrical activity of the brain of the individuals in response to a specific sequence of stimuli in generating data sets, which, for example, can be encapsulated as a data structure. The data sets can include tracked specific response types, at different times and amplitudes, including, but not limited to, event related potential signal components. Brainwave features including, event related potentials, are...

SYSTEMS, METHODS, AND KITS FOR PERIPHERAL NERVE STIMULATION

University of Toronto

Nerve stimulation systems and methods are disclosed for providing modulation of nerve targets in the lower limbs typically at or below the knee. For example, transcutaneous electrical nerve stimulation (TENS), percutaneous nerve stimulation, and implantable stimulation systems and methods are disclosed for providing stimulation to the saphenous nerve (SAFN). Additionally, systems and methods are provided for co-stimulating the posterior tibial nerve (PTN) and SAFN in combination with unique...

EXPERT SYSTEM FOR DETERMINING PATIENT TREATMENT RESPONSE

McMaster University

A medical digital expert system to predict a patient's response to a variety of treatments (using pre-treatment information) is described. The system utilizes data fusion, advanced signal/information processing and machine learning/inference methodologies and technologies to integrate and explore diverse sets of attributes, parameters and information that are available to select the optimal treatment choice for an individual or for a subset of individuals suffering from any illness or...

SYSTEMS AND METHODS OF ENHANCING ELECTRICAL ACTIVATION OF NERVOUS TISSUE

University of Toronto

Methods and systems for improving nerve stimulation are disclosed and are termed enhanced transcutaneous electrical stimulation (eTENS). One embodiment can be used for enhancing the excitation properties of neural tissue. In one embodiment, systems and methods are provided to enable the selective modulation of specific (targeted) neural substrate, while minimizing the activation of adjacent (non-targeted) nervous tissue, or differentially providing different modulation signals to tissue...

METHODS FOR MODULATING NEURONAL RESPONSES

University of British Columbia

The invention provides, in part, methods and reagents for modulating neuronal apoptosis and for modulating synaptic plasticity.

SYSTEMS AND METHODS FOR TREATMENT OF URINARY DYSFUNCTION

University of Toronto

Methods and systems for providing therapy related to urological disorders are described. Particular embodiments of this technology relate to stimulation of the saphenous nerve (SAFN) either alone or in combination with the posterior tibial nerve (PTN), medial plantar nerve (MPN) or lateral planar nerve. In embodiments nerves are stimulated by percutaneous, transcutaneous, and/or implanted stimulators. In embodiments the SAFN is stimulated below the level of the knee or near the medial...

GB1 PEPTIDIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME

REFLEXION PHARMACEUTICALS, THE UNIVERSITY OF CHICAGO, University of Toronto

GB1 peptidic compounds that specifically bind to a target molecule are provided. Both L-peptidic and D-peptidic compounds are included. In some embodiments, the subject compounds include a GB1 motif and one or more extension moieties connected to the N-terminal or C-terminal of the GB1 motif via optional linkers. The extension moieties may be peptidic, and as such may include a protein domain, or a peptidic sequence of up to 50 residues. Also provided are GB1 multimers that include two or...

METHOD AND SYSTEM FOR IMPROVING A SUBJECT'S SENSORY, REFLEX AND/OR MOTOR MECHANISMS VIA AUDITORY, TACTILE OR VISUAL STIMULATIONS

University of Montreal

The present invention relates to a method and a system for improving sensitivity of a first sensory, reflex and/or motor mechanism of a subject by stimulating a second sensory, reflex and/or motor mechanism of the subject. For that purpose a noise is applied to the second sensory, reflex and/or motor mechanism to improve the sensitivity of the first sensory, reflex and/or motor mechanism due to cross-modal SR interactions.

METHOD OF THERAPY AND HAPTIC GAMING SYSTEM FOR SENSORY AGNOSIA

FLINDERS UNIVERSITY OF SOUTH AUSTRALIA, University of South Australia, WOMEN'S AND CHILDREN'S HEALTH NETWORK

A method for treating patients with sensor agnosia is described that uses a gaming system with a specialised two handed game controller that can provide isolated haptic feedback to the patient's hand that has the greatest sensory agnosia. The controller is designed to be easy to use for patients with limited dexterity and requires the user to use both hands to control the controller. The gaming system provides a range of interactive computer games that provide contextually relevant haptic...

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