Leluo Guan

Key Research Areas
Associated Researchers
Associated Organizations

Recent Research Projects

A novel approach to improve gastrointestinal tract function in ruminants

2016/17-2018/19 • $239,161 • PI,CO
Promoting gastrointestinal health is an important strategy to improve the efficiency for livestock production. Recently, it has been recognized that nutrients can elicit a greater response than expected based on nutrient supply alone. In many cases, it is suggested that such functional nutrients...

Understanding the impact of the host on microbial ecology and host functions in the gastrointestinal tract of calves using functional genomics

2013/14-2018/19 • $200,000 • PI
The mammalian gastrointestinal tract (GIT) harbours dynamic and abundant microbial populations and such populations are rapidly established during and immediately after birth. There is increasing evidence that commensal microbiota plays an important role in the development of the GIT epithelial...

A flow cytometer/sorter for agricultural and food science research

2017/18 • $146,214 • PI,CO
A flow cytometer/cell sorter is requested to promote research and innovation in agricultural and food science in the Department of Agricultural, Food and Nutritional Science, University of Alberta. This equipment will benefit multiple internationally recognized research programs in the areas of...

Development of a nucleic acid based assay to monitor and quantify viable yeast cells

2017/18 • $25,000 • PI
Cattle industry is one of the major Canadian agriculture sectors, which provides the animal proteins (milk andmeat) to humans. Recently, the direct fed microbes have been considered as one of the powerful approaches tohave long term effect to improve the animal productivity and health through...

Pyrosequencer for genomics and epigenomics research

2016/17 • $103,234 • PI,CO
A multi-user core facility, Agricultural Genomics and Proteomics Unit (AGP Unit), in the Department of Agricultural, Food and Nutritional Science, provides key capacity for researchers employing genomics technologies for technological innovation in food and the bio-economy. These internationally...

Effect of TASCO, a seaweed extract on rumen functions of ruminants: microbial diversity and activities in sheep

2014/15-2015/16 • $70,000 • PI
Improvement of animal's production and health is vital to enhance the sustainability of Canadian livestock industry. The rumen is a capacious pre-gastric anaerobic fermentation chamber sustaining a rich community of microorganisms that rapidly colonize and digest feed particles. The rumen and...

Supplementation with Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) to Prevent Sarcopenia and Myosteatosis

2011/12-2014/15 • $438,708 • PI,CO
This proposal stems from our recent observations that muscle wasting is common in people with cancer. Often, muscle loss associates with increased content of fat in muscle. Each of these features is related to morbidity and survival in people with cancer. Here, we propose new basic research to...

Variable Mode Laser Scanner for Precise Imaging and Quantitation of Biomolecules

2014/15 • $110,111 • PI,CO
Agricultural Genomics and Proteomics Unit (AGP Unit) in the Department of Agricultural, Food and Nutritional Science is a multi-user core facility supporting the research programs of over 100 users from The Livestock Gentec Group, The Swine Reproduction-Development Program, Alberta Innovates...

Epigenetic effects of early life antibiotics on genes relevant for metabolic disease and immune tolerance

2013/14 • $100,000 • PI,CO
A large proportion of Canadian infants are exposed to antibiotics in early life. Although critical for treating some bacterial infections, antibiotic exposure during the early developmental period is associated with an increased risk of obesity later in life. There is an abundant population of...

Effect of TASCO, a seaweed extract on rumen functions of ruminants

2013/14 • $25,000 • PI
Improvement of animal's production and health is vital to enhance the sustainability of Canadian livestockindustry. The rumen is a capacious pre-gastric anaerobic fermentation chamber sustaining a rich community ofmicroorganisms that rapidly colonize and digest feed particles. The rumen and its...

Characterization of methanogens and their key genes associated with methane production in beef cattle: linkage to host performance

2010/11-2012/13 • $70,050 • PI
It is well known that ruminants and ruminal microorganisms have a symbiotic relationship which microbial fermentation of ingested feed plays a major role in supplement of energy for metabolic functions in cattle. The rumen of cattle can be considered as an active "bio-reactor" producing many...

Microplate reader, a necessary tool for functional genomics and proteomics studies in animal, microbial and plant systems

2011/12 • $38,755 • PI,CO
High throughput functional genomics and proteomics studies are the major focus of the research conducted in a multi-user Agricultural Genomics and Proteomics Unit (AGP Unit) in the Department of Agricultural, Food and Nutritional Science. Various researchers from The Livestock Genomics Group,...

Ozone free box for microarray based functional genomics studies

2010/11 • $22,227 • PI,CO
High throughput functional genomics and proteomics studies are the major focus of the research conducted in a multi-user Agricultural Genomics and Proteomics Unit (AGP Unit) in the Department of Agricultural, Food and Nutritional Science. Various researchers from The Alberta Ingenuity Centre for...

Patents