Adi Steif

Contact via University of British Columbia

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Recent Research Projects

Clonal evolution and acquired drug resistance in breast cancer patient xenografts profiled at single cell resolution

2015/16-2017/18 • $150,000 • Scholarship/Fellowship,Other
Cancer is the leading cause of death in Canada and worldwide. Cancer tumours generally arise from a single cell which has acquired genetic mutations leading to uncontrolled cell division. As cancer cells divide, they acquire additional mutations which are passed down to their descendents. Drug...

RNA Secondary Structure and Gene Expression Modulation in Trypanosomes

2012/13 • $17,500 • Scholarship/Fellowship
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Methods, devices and systems for analyzing precious samples of cells, including single cells are provided. The methods, devices, and systems in various embodiments of the invention are used to assess genomic heterogeneity, which has been recognized as a central feature of many cancers and plays a critical role in disease initiation, progression, and response to treatment. The methods devices and systems are also used to analyze embryonic biopsies for preimplantation genetic diagnosis (PGD)....
Related applications: CA20162974632, EP20160746018, EP20200197858