Eric Beamish

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Recent Research Projects

Multiplexed Detection of Disease Biomarkers Using Solid-State Nanopores

2013/14-2015/16 • $63,000 • Scholarship/Fellowship
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Patents

METHOD FOR CONTROLLING THE SIZE OF SOLID-STATE NANOPORES

A method is provided for precisely enlarging a nanopore formed in a membrane. The method includes: applying an electric potential across the nanopore, where the electric potential has a pulsed waveform oscillating between a high value and a low value; measuring current flowing though the nanopore while the electric potential is being applied to the nanopore at a low value; determining size of the nanopore based in part on the measured current; and removing the electric potential applied to...
Related applications: WO2013IB00884, EP20130787360, EP20130787360, ES20130787360T, CA20132872600

INTEGRATING NANOPORE SENSORS WITHIN MICROFLUIDIC CHANNEL ARRAYS USING CONTROLLED BREAKDOWN

Nanopore arrays are fabricated by controlled breakdown in solid-state membranes integrated within polydimethylsiloxane (PDMS) microfluidic devices. This technique enables the scalable production of independently addressable nanopores. By confining the electric field within the microfluidic architecture, nanopore fabrication is precisely localized and electrical noise is significantly reduced during sensing.
Related applications: CA20152970627, WO2015IB59799, EP20150869455