Manon Couture

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Recent Research Projects

Biochemical and functional characterization of proteins and enzymes for heme-iron acquisition and utilisation in bacteria

2019/20 • $32,000 • PI
Characterization of proteins of poorly understood pathways from microorganisms is important to increase our knowledge of biological processes, to discover new protein functions and to identify new protein targets, which are highly desirable to help the development of much needed new...

Mechanisms of molecular oxygen and peroxide activation by the nitric oxide synthases and the heme degrading enzyme ChuS

2012/13-2016/17 • $170,000 • PI
The long term goal of my research program is to detail at the molecular level the kinetic mechanisms of heme enzymes, i.e. enzymes that use heme as a cofactor. Heme enzymes play numerous important functions such as the degradation of xenobiotics, synthesis of sexual hormones, bioremediation,...

Cell Grower : High-throughput measurements of microbial growths

2016/17 • $77,425 • PI,CO
Monitoring microbial cell growth is central to many fields of research, including systems biology, genomics, evolution, microbial ecology, enzyme kinetics and crystallography as well as the study of bacterial and fungal pathogens. With the increase in throughput in all the fields of...

The mechanisms of nitric oxyde synthesis by nitric oxide synthases

2010/11-2011/12 • $84,000 • PI
Nitric oxide synthases (NOSs) synthesize the signaling and oxidative stress molecule nitric oxide (NO). The long-term objectives of this research program are to determine the structural, functional and dynamic properties of the active site of NOSs to understand the catalytic cycle and mechanisms...

Spectrophotomètre pour cinétiques enzymatiques

2011/12 • $61,376 • PI,CO
Cette demande en équipement permettra l'acquisition d'un spectrophotomètre Cary et de répondre à un besoin majeur pour des chercheurs tous subventionnés par le CRSNG. L'équipement demandé fera partie du parc d'appareils disponibles à l'Institut de biologie intégrative et des systèmes (IBIS) créé...