Alfredo Capretta

Key Research Areas
Associated Researchers
Associated Organizations

Recent Research Projects

NSERC CREATE Biointerfaces Training Program

2011/12-2016/17 • $1,300,000 • PI,CO
Our understanding of the nature of the biological/material interface, or biointerface, impacts all materials in biological media from contact lenses to blood contacting materials to diagnostic test strips and new bioseparation media. The CREATE Biointerfaces Training Program will provide unique...

NSERC CREATE Molecular Imaging Probes training program (CMIP)

2012/13-2015/16 • $1,200,000 • PI,CO
The impact that was felt by the recent shortage of medical isotopes highlighted the importance that molecular imaging and the associated probes has on the health of Canadians and on the economy of Canada. It also demonstrated that there is a need to train a new generation of scientists to...

Overcoming antibiotic resistance through the inhibition of aminoglycoside phosphotransferases (APH).

2013/14-2014/15 • $169,101 • PI,CO
Multidrug resistant microbes have become one of the top global health challenges and place a massive burden on theCanadian health care system. One approach to overcome this problem involves inhibiting the enzymes responsible forconferring resistance to the antibiotic. We have recently discovered...

The CREATE Molecular Imaging Probes Program

2010/11-2011/12 • $450,000 • PI,CO
The impact that was felt by the recent shortage of medical isotopes highlighted the importance that molecular imaging and the associated probes has on the health of Canadians and on the economy of Canada. It also demonstrated that there is a need to train a new generation of scientists to...

Patents

PROCESS FOR THE PREPARATION OF 2-[2-(2-AMINO-2-CARBOXY-ETHYLAMINO)-2-CARBOXY-ETHYLAMINO]-SUCCINIC ACID (AM-A) AND ANALOGS AND DERIVATIVES THEREOF

The present application relates to processes for the preparation of the aspergillomarasmine A (AM-A) compound and analogs and derivatives thereof. The features of this process involves the use of a cyclic activated serine synthon in the construction of the poly-amino acid backbone. Also included are certain novel analogs of AM-A along with compositions comprising these compounds and uses thereof.
Related applications: WO2016CA51259