Vilceu Bordignon

Key Research Areas
Associated Researchers
Associated Organizations

Recent Research Projects

Genome Editing for Food Security and Environmental Sustainability

2019/20 • $150,000 • PI,CO
Animal biotechnology,cispr,climate change,experential learning,food security,genome editing,plant biotechnology,policy and regulation,public perception,sustainability

Cell reprogramming, embryo development and genome integrity

2016/17-2019/20 • $140,000 • PI
Cell differentiation and reprogramming are important research topics for the study of disease mechanisms and development of new cell-based therapies. Somatic cell nuclear transfer (SCNT) into enucleated oocytes was the original method used to confirm that differentiated somatic cells retain...

Development of Methods for the Consistent Production of Transferable Embryos from Oocytes Collected from Mediterranean Buffalo Donors at Prepubertal Ages

2019/20 • $25,400 • PI
There is a growing demand for buffalo dairy products that cannot be met because of the limited number of females of good milk productivity available in Canada and the very long time it takes for these animals to achieve sexual maturity. Assisted reproductive technologies such as artificial...

Improving gene-editing protocols for application in swine production

2018/19 • $25,000 • PI
Genome editing, the technology to turn on/off/correct genes at an embryonic stage of development, is viewed*by front-runners such as Alphagene-Olymel as "the key to the future", in terms of accelerated genetic*improvement and increased production efficiency. In fact, recent development of genome...

Development of new protocols for prepubertal reproduction of water buffalos using laparoscopic ovum pick-up and in vitro embryo production technologies

2016/17 • $25,000 • PI
Assisted reproductive technologies such as artificial insemination, embryo transfer, in vitro embryo productionand sex-sorted semen have become important tools in bovine breeding and selection programs. However, thesetechnologies have not been entirely adapted to buffalos. There is growing...

Somatic cell reprogramming by nuclear transplantation

2011/12-2015/16 • $150,000 • PI
Somatic cell nuclear transfer (SCNT) into enucleated oocytes has outstanding applications in research to study different cellular processes, as well as practical applications for cloning animals (e.g., save endangered species, replicate genetically superior animals, produce genetically modified...

Optimized sperm injection technologies for in vitro embryo production in cattle

2014/15-2015/16 • $140,000 • PI
The field of this proposed research is advanced reproduction technologies in cattle. Sperm injection technologies (SIT), in which a single sperm is injected inside an egg to achieve fertilization in vitro, are very successfully used to treat male infertility in human clinics around the world....

Integrated System for Editing Eukaryotic Genomes

2015/16 • $117,239 • PI,CO
Recent developments using engineered “meganucleases”, particularly those based on the CRISPR/Cas system, have revolutionized research requiring targeted gene modifications. This technology has dramatically increased the efficiency and reduced the cost and time it takes to genetically...

Next Gen Sequencing Platform for Environmental Sciences

2014/15 • $125,635 • PI,CO
The ability to rapidly sequence nucleic acids through high throughput next-generation sequencing (NGS) technology is having an enormous impact on every area of biology. The ability to rapidly perform genomic/transcriptomic, metagenomic/metatranscriptomic, and microbial community profiling is now...

Functional Feed Supplement with Plant Polyphenols for the Improvement of Health, Reproductive Performance, and Milk Production in the Transition Period of Dairy Cows - Phase 2

2014/15 • $12,500 • PI
Outstanding genetic improvements in milk production have been accomplished at the cost of an excessivemetabolic demand on dairy cows. The impact of such demand is most evident during the so-called transitionperiod when the cow needs to finalize the development of a rapidly growing fetus, give...

NSERC EmbryoGENE Strategic Network

2010/11-2013/14 • $3,452,850 • PI,CO
No summary

Functional feed supplement with plant polyphenols for the improvement of health, reproductive performance, and milk production in the transition period of dairy cows

2013/14 • $25,000 • PI
Outstanding genetic improvements in milk production have been accomplished at the cost of an excessivemetabolic demand on dairy cows. The impact of such demand is most evident during the so-called transitionperiod when the cow needs to finalize the development of a rapidly growing fetus, give...

Optimization of an intracytoplasmic sperm injection protocol for the in vitro production of bovine embryos using sex-sorted semen

2012/13 • $25,000 • PI
Assisted reproductive technologies such as artificial insemination, embryo transfer, in vitro embryo production and sex-sorted semen have become important tools in bovine breeding and selection programs. More recently, there is a growing interest in the use of intracytoplasmic sperm injection...

Immunological sexing of porcine semen: optimization of sperm separation conditions followed by confirmation by in vitro embryo production and PCR sexing

2011/12 • $25,000 • PI
The objective of this research is to investigate the use of small antibodies (single domain antibodies or nanobodies) for the separation of pig spermatozoa carrying either an X or Y chromosome. The partner company in this research project, AB Biotech Inc, has developed a method to produce...

Patents