MarcAndré Sirard

Key Research Areas
Associated Researchers
Associated Organizations

Recent Research Projects

Chaire de recherche du Canada en génomique fonctionnelle appliquée à la reproduction animale

2014/15-2019/20 • $1,050,000 • PI
The Chair program was at the root of an international leadership position in the field of reproductive genomics. We created a national embryo consortium in 2000-2005 which became international with the NSERC strategic network EmbryoGENE from 2008-2014. This program was key to the building of the...

Programming the oocyte for the next generation

2014/15-2019/20 • $576,000 • PI
This research program is focused on the most extraordinary cell of the body: the oocyte. Indeed this cell has unique capacities as, in the weeks preceding ovulation, it accumulates instructions in order to control/allow early embryonic development following fertilization. This exceptional...

Génomique de précision en agriculture

2019/20 • $141,516 • PI,CO
Cette demande vise l'acquisition d'un PCR digital pour accélérer et bonifier nos activités de recherche dans le domaine de la transcriptomique en agriculture. Nous utilisons actuellement différentes plateformes technologiques qui permettent une analyse de l'expression des gènes (micro-puces,...

DNA methylation biomarkers of fertility in bulls

2018/19-2019/20 • $75,300 • PI
Fertility in dairy cows has become a real concern despite the progression made in genetic selection to alleviate this phenotype. One of the possible explanations for the increased prevalence of mild infertility could be the epigenetic programming that would act in addition to genetic...

Bovine imprinted gene analysis in assisted reproduction techniques

2018/19-2019/20 • $60,000 • PI
The production of bovine embryos through in vitro maturation and fertilization is becoming an important tool of the genomic revolution in dairy cows. The capacity to select embryos based on the father and the mother genotypes and the possibility to do that at the blastocyst level before a...

Traitement ciblé de l'infertilité post-partum chez la vache laitière

2018/19-2019/20 • $33,902 • PI,CO
Un des enjeux majeurs en production laitière est lié au fait que les vaches ont une fertilité réduite particulièrement dans les 2-3 mois qui suivent la parturition et malheureusement souvent chez les fortes productrices. Si le problème est bien connu , la cause, elle, demeure ambigue. De...

Démonstration des effets biologiques et économiques de repousser l'insémination des vaches en stress métabolique/nutritionnel du jour 60 au jour 120 post-partum

2016/17-2018/19 • $54,827 • PI,CO
Ce projet réuni des expertises complémentaires de la génomique et de l'économique appliquées aux bovins laitiers. L'Université Laval en partenariat avec Valacta et Novalait collaboreront pour documenter un phénomène en émergence, soit la programmation épigénétique intergénérationnelle et ses...

Perfect follicles for perfect oocytes (PFPO)

2014/15-2016/17 • $222,000 • PI,CO
Canada's position as a leader in dairy genetics has been gained through excellent selection, good genetics and the development of assisted reproductive technologies, which involved innovative donor management practices and laboratory breakthroughs. Through these innovations, Canadian producers...

Epigenetic and transcriptomic analysis of embryos from oocytes or sperm from peri-pubertal bovine

2013/14-2015/16 • $197,800 • PI,CO
The selection pressure in dairy cow reproduction is resulting in the use of younger animals for reproductive purposes both in the male and the female. One of the limiting parameter is the normal physiology of the brain at puberty which controls the maturation of gametes in both sexes. Although...

NSERC CREATE Training Program in Reproductive Biology

2010/11-2014/15 • $1,500,000 • PI,CO
The overall objective of the program is to create a new, novel, superior and sustainable research training and mentoring environment to form the next generation of reproductive and developmental biologists. This will be achieved by providing multi-institutional, transdisciplinary training from...

Canadian research Chair in animal reproduction genomics

2010/11-2014/15 • $950,000 • PI
No summary

NSERC EmbryoGENE Strategic Network

2010/11-2013/14 • $3,452,850 • PI,CO
No summary

Molecular green light to next generation

2010/11-2013/14 • $384,000 • PI
This research program is exploring the most extraordinary cell of the body, the oocyte. Indeed this cell has unique capacities and properties. Firstly, this cell does not age as other cells in our body and has the ability to rejuvenate an adult cell when fused with it. Secondly this cell...

Infertility biomarkers: the link between genomic and genetic

2010/11-2012/13 • $95,625 • PI,CO
No summary

Follicles to eggs

2010/11-2011/12 • $130,290 • PI,CO
Although major advances were made recently in the field of reproductive technologies, we are still far from understanding all the molecular events that regulate and control the quality of eggs that will develop into healthy embryos. Recent studies clearly established that oocytes acquire their...

The use of genomic-genetic tools to improve dairy cow reproduction

2011/12 • $13,930 • PI,CO
Industry-wide selection for cows with dairy character (grouping of body traits found to correspond with milk production) has had a negative impact on the fertility of dairy cows. Animal's reproductive ability is an important component of an efficient dariy herd management. Unless a cow can...