Mathieu Roy

Contact via McGill University

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Recent Research Projects

Central nervous system mechanisms underlying the effects of exercise therapy on chronic low back pain .

2018/19-2020/21 • $463,224 • PI,CO
It is estimated that approximately 20% of the Canadian population is currently suffering from chronic pain. Amongst the different chronic pain syndromes, chronic low back pain (CLBP) is by far the most prevalent, and the one responsible for the most years lived with disability. Alas, we still...

Brain imaging of experimental and chronic pain

2018/19-2020/21 • $310,000 • PI
Unspecified/Non Spécifié

Decision making impairments in psychiatric disorders: testing the trans-diagnostic role of interoception.

2017/18-2020/21 • $221,250 • Scholarship/Fellowship,Other
The ability to make optimal decisions is often altered in mental health conditions such as autism, eating disorders, substance addiction and depression. This impairment could contribute to the rigid and maladapted behaviours sometimes observed in these conditions. For example, persons with these...

Long-lasting effects of oral contraceptive use during adolescence: An investigation of neural, endocrine, and cognitive systems

2020/21 • $98,685 • PI,CO
Oral contraceptive pill (OCP) is a largely used contraceptive method that is often prescribed during adolescence, a time at which the brain is still developing. OCP is composed of synthetic sex hormones, which abolish the menstrual cycle and maintain very low levels of endogenous sex hormones....

When Pain Drives you N. U. T. S.: A mixed methods approach to investigating triggers of the stress response and multidimensional pain outcomes in a sample of individuals suffering from chronic low back pain

2020/21 • $89,251 • PI,CO
One in five Canadian suffers from chronic pain. Psychological factors play an important role in the perception, development and maintenance of chronic pain. These factors however are often examined without considering the nature of the pain experience that could influence these psychological...

Psychological and neurobiological determinants of opioid-related problems and opioid tapering outcomes among patients with chronic pain prescribed long-term opioid therapy

2020/21 • $84,151 • PI,CO
Chronic pain is a major health problem that affects approximately 20 % of the Canadian population. There has been an increase in the use of opioid medications for the management of chronic pain over the past decade in Canada, but this has been paralleled by escalating rates of opioid addiction...


2016/17-2019/20 • $132,000 • PI
Pain signals the presence of an urgent threat to our corporal integrity; it calls for our complete attention and commands immediate action. However, pain also marks an error in the long chain of decisions that ultimately led us to expose ourselves to danger. Pain therefore also compels us to...

Could brain stimulation alleviate chronic low back pain and potentiate the effect of exercises?

2019/20 • $99,975 • PI,CO,Other
Back pain produces the most years lived with disability in Canadian population. Despite continuous research effort, the prevalence of chronic back pain continues to grow, and the effect of conventional interventions on pain and disability is modest causing an enormous individual, social and...

Beyond pain subjectivity: A neuroimaging investigation of multidimensional pain-responses and their related function

2013/14-2018/19 • $689,014 • PI,CO
Pain is a fundamental experience thought to reflect the vital biological function of the nociceptive system in the protection of the body. This experience is accompanied by a variety of physiological reflexes (e.g. withdrawal, sweating), and behavioral responses (e.g. facial expression) that...

An investigation of the effects of physical exercise on the central nervous system processes underlying the maintenance of chronic low back pain.

2016/17 • $100,000 • PI,CO
Approximately 20 % of the Canadian population is currently living with chronic pain, which is defined as pain that lasts for more than 6 months. Amongst chronic pain syndromes, low back pain is the most prevalent. Unfortunately, current treatments only have relatively modest effects on pain....

Validation of separate pain biomarkers using combined fMRI and TMS

2011/12-2014/15 • $203,334 • Scholarship/Fellowship,Other
Pain is a fundamentally subjective experience. As a result, subjective pain ratings have proven to be the most reliable indexes of pain. Nevertheless, pain ratings are still subjected to the same biases as other self-reported measures. The proposed experiment is part of a larger project aiming...