Jonathan R. Yeh

Key Research Areas
Associated Researchers
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Recent Research Projects

Identifying therapeutic targets of the Hox-Meis network that regulate leukemia stem cell fate.

2013/14-2015/16 • $88,556 • Scholarship/Fellowship,Other
Acute myeloid leukemia (AML) is diagnosed annually in ~1,200 patients in Canada. Treatment for this disease has not changed significantly over the last 30 years and the overall survival of AML patients remains close to 20%. Unfortunately, most AML patients relapse within 3 years of diagnosis and...

Patents

COMPOUNDS AND USE THEREOF IN THE EXPANSION OF STEM CELLS AND/OR PROGENITOR CELLS

The invention relates to compounds of formula I and pharmaceutical compositions containing them. Also, the invention relates to methods for expanding stem cells and/or progenitor cells and methods for treating a hematopoietic disorder/malignancy, and autoimmune disease and/or an inherited immunodeficient disease (I).
Related applications: WO2018IB58593