Catherine A. Lebel


Contact via University of Calgary


Key Research Areas
Associated Researchers
Associated Organizations

No partner organizations found.

Recent Research Projects

Advancing Concussion Assessment and Treatment in Children and Youth

2015/16-2020/21 • $3,341,337 • PI,Other
Each year, millions of children sustain concussions/mild traumatic brain injuries (mTBI), and 15-25% suffer persistent symptoms and declines in quality of life. Clinicians caring for these children face three critical, unanswered questions: how to diagnose concussion, how to predict which...

Bridging the Gap in Paediatric Traumatic Brain Injury: Environmental, biological and clinical markers associated with preschool concussion and TBI

2016/17-2020/21 • $981,156 • PI,Other
Concussions and other traumatic brain injuries are a frequent cause of death and disability in youth, and children under the age of 6 are at particularly high risk. Older children with brain injuries often suffer serious mental, psychological, social, and behaviour problems. Even mild injuries...

Contribution of the microbiome to asthma risk in premature infants

2019/20-2020/21 • $608,385 • PI,CO,Other
Premature infants are at increased risk of life-long diseases and treatments. Among the most compromised organs of premature infants are the lungs. In Canada and globally, very premature infants (between 28-32 weeks of gestation) and extremely premature infants (less than 28 weeks of gestation)...

Role of the gut microbiota and physiological systems underlying internalizing problems during the transition from childhood to adolescence

2019/20-2020/21 • $376,502 • PI,CO
The human gut is colonized by trillions of bacteria that play a role in human health and disease. Recent animal and human evidence shows that communication between the gut microbiota and the brain has the ability to influence behavior and mood. Although it isn't entirely clear how this happens,...

Brain development and internalizing symptoms in youth with fetal alcohol spectrum disorder

2019/20-2020/21 • $370,252 • PI,CO
Fetal alcohol spectrum disorder (FASD) is caused by prenatal exposure to alcohol, and affects 4% of individuals in Canada. Key features of FASD are learning, growth and behaviour problems, and most people with FASD (>90%) also have mental health problems. Depression and anxiety are among the...

Pediatric Neuroimaging

2018/19-2020/21 • $310,000 • PI
Unspecified/Non Spécifié

Magnetic resonance imaging of pediatric brain development

2015/16-2020/21 • $300,000 • PI
Neurodevelopmental disorders are becoming increasingly more prevalent. Some of the more common disorders include dyslexia (affecting approximately 5-17% of children), fetal alcohol spectrum disorder (2-5%), attention deficit hyperactivity disorder (3-11%) and autism spectrum disorder (~1.5%)....

Elucidating the Role of Memory in the Transition from Acute to Chronic Pediatric Pain

2020/21 • $132,345 • PI,CO
How children remember pain sets the stage for future pain experiences. These memories can easily become distorted. Negatively-biased pain memories (remembering pain as being worse than an earlier pain report) are associated with the development of pediatric chronic pain. Pediatric chronic pain...

Social adjustment in survivors of pediatric acute lymphoblastic leukemia (ALL)

2019/20-2020/21 • $110,430 • PI,CO
Background: Acute lymphoblastic leukemia (ALL) is a cancer that affects the white blood cells and is the most common cancer affecting children. Thanks to many advances in treatment, most children diagnosed with ALL will survive. The treatments needed to cure ALL, however, are toxic because they...

Social Competence in Children Diagnosed with Sickle Cell Disease: An examination of risk factors

2018/19-2020/21 • $107,728 • PI,CO
Background: Sickle cell disease (SCD) is a severe, genetic form of anemia that causes distorted red blood cells. The distorted red blood cells can impact almost every tissue in the body and cause a number of difficulties including pain, risk of stroke, learning difficulties, decreased quality of...

Prenatal maternal physical activity and brain structure and function in young children

2019/20-2020/21 • $82,822 • PI,CO
Physical activity during pregnancy can be good for both the mother and the baby. Yet fewer than 2 in 10 pregnant women meet the Canadian guidelines of at least 150 minutes of moderate activity per week. Children of mothers who were more active during pregnancy appear to have better learning and...

Social adjustment in survivors of pediatric acute lymphoblastic leukemia (ALL)

2020/21 • $76,500 • PI,CO
Background: Acute lymphoblastic leukemia (ALL) is a cancer that affects the white blood cells and is the most common cancer affecting children. Thanks to many advances in treatment, most children diagnosed with ALL will survive. The treatments needed to cure ALL, however, are toxic because they...

Language ability and structural brain development in preschool children: predictors of reading readiness

2014/15-2019/20 • $991,469 • PI,CO
Problems with language and reading are common in children, and can lead to lifelong difficulties in school and adult life (i.e., career). Structural brain abnormalities are associated with reading problems in school-aged children, and these abnormalities might exist before reading begins....

Brain Development and Reading Acquisition in Preschool Children

2019/20 • $21,250 • Scholarship/Fellowship,Other
Brain development supports numerous cognitive and behavioural functions, including language and reading. Early childhood (2-7 years) is a critical period for the acquisition of language and reading skills, yet we currently have a limited understanding of brain development in this age range due...

The microbiome of premature infants in asthma risk

2018/19 • $25,000 • PI,CO
Premature infants face an increased risk for life-long diseases and treatments. Among the most compromised systems of premature infants is the lung function. In Canada and globally, very premature infants (between 28-32 wks gestation) and extremely premature (less than 28 wks gestation) babies...

Developmental Origins of Sex-Differentiated Mental Disorders in Children: Social, Epigenetic and Neurologic Factors

2015/16 • $9,933 • PI,CO
Most adults with mental disorders report that they remember symptoms from childhood. Symptoms typically include childhood internalizing (e.g. anxiety, depression) and externalizing (e.g. hyperactivity, aggression) behavioural problems, the focus of this Team Grant. Girls experience more...

Language ability and structural brain development in preschool children: predictors of reading readiness

2013/14 • $100,000 • PI,CO
Problems with reading are common in children, and can lead to lifelong difficulties learning and in adult life (i.e., career). Early identification of reading problems allows for early treatments, which are more effective than later interventions. Currently, reading problems are not diagnosed...

Magnetic resonance imaging of brain development in children and youth with perinatally-acquired HIV

2011/12-2012/13 • $134,167 • Scholarship/Fellowship,Other
Human immunodeficiency virus (HIV) is the virus that causes acquired immunodeficiency syndrome (AIDS), which ultimately leads to immune system failure. HIV can be transmitted in several ways, including from an infected mother to her child during pregnancy, labour, delivery, or breast-feeding...

Patents