Brian K. Kwon


Contact via University of British Columbia


Key Research Areas
Associated Researchers
Associated Organizations

Recent Research Projects

Neuron-Glia interactions in brain disease

2016/17-2019/20 • $1,735,649 • PI,Other
The goal of my research is to prevent neuronal death and brain impairment that occurs following stroke and during neurodegeneration. My work in the past has shown that the preservation of a healthy brain requires communication between the nerve cells and the surrounding cells termed glia, such...

Spinal Cord Injury

2018/19-2019/20 • $200,000 • PI
Unspecified/Non Spécifié

Spinal Cord Injury

2013/14-2017/18 • $500,000 • PI
Each year, over 1000 Canadians sustain an acute spinal cord injury (SCI), and join close to 40,000 across our nation living with one of the most physically and psychologically devastating of injuries that one can survive. Unfortunately, we currently have no treatments to regenerate the injured...

Biomechanical factors in spinal cord injury - relevance to the timing of decompression

2014/15-2017/18 • $423,361 • PI,CO
Spinal cord injuries (SCIs) are caused primarily by high-speed injury to the body where severe forces are exerted on the human neck, which result in various patterns of bony injury to the neck. Further, recent research by our group has shown that these different patterns of bony injury also...

Hemodynamic Support in Traumatic Spinal Cord Injury: Effects on Metabolism, Inflammation, and Functional Outcome.

2014/15-2016/17 • $395,064 • PI,CO
Each year, over 1,700 Canadians are paralyzed after suffering an acute traumatic spinal cord injury (SCI). Unfortunately, current treatment options for acute SCI are extremely limited. These include surgical decompression to relieve pressure on the cord, and support of systemic blood pressure to...

Ketogenic Diet for Spinal Cord Injury - Preclinical Studies

2012/13-2015/16 • $225,000 • PI,CO
About 4 million people worldwide live with paralysis from traumatic spinal cord injury (SCI) and an estimated 200,000 SCI occur every year. Yet there is no cure and treatment is limited to surgery to stabilize the spine, and physical rehabilitation. We found that rats recover better from spinal...

Stem cells to treat spinal cord injury

2010/11-2013/14 • $1,732,962 • PI,CO
Each year, approximately 1000 Canadians sustain an acute traumatic spinal cord injury and join close to 40,000 paralyzed individuals across our nation who endure one of the most physically and psychologically devastating of injuries. We have recently shown that two novel populations of stem...

A Translational Approach to Neuro-Inflammation and Behavioral Outcomes After Spinal Cord Injury

2010/11-2013/14 • $240,000 • PI
Spinal cord injuries result in devastating paralysis, often in young, otherwise healthy individuals. A great deal of scientific research into spinal cord repair/regeneration has been conducted over the past 30 years, offering much hope to individuals with this catastrophic injury. Despite this,...

Clinically relevant mechanisms of spinal cord injury

2010/11-2012/13 • $485,822 • PI,CO
Spinal cord injury (SCI) is a major public health problem, devastating for the afflicted individuals and very costly for our health care system. SCI begins with mechanical insult to the cord (i.e. primary injury), followed by a series of biological events that further damage the cord. The...

A Translational Approach to Neuro-Inflammation and Functional Outcomes After Human Spinal Cord Injury

2010/11-2011/12 • $234,296 • PI,CO
Spinal cord injuries result in devastating paralysis, often in young, otherwise healthy individuals. A great deal of scientific research into spinal cord repair/regeneration has been conducted over the past 30 years, offering much hope to individuals with this catastrophic injury. Despite this,...

The role of cerebrospinal fluid and the subarachnoid space in acute spinal cord injury

2010/11 • $19,569 • PI
Spinal cord injury (SCI) is severe and debilitating with significant personal, social and economic costs.The complex mechanical interactions between the spinal cord and the surrounding cerebrospinal fluid (CSF) and dura both during and immediately following SCI are not understood. Therefore, the...

Patents

METHODS AND APPARATUS FOR NEAR INFRARED SPECTROSCOPY

A system for performing near infrared spectroscopy (NIRS) monitors tissue oxygenation and/or hemodynamics. The system comprises a sensor coupled to a controller and/or processing device. The sensor comprises a light source which is operable to emit light of various distinct wavelengths and a detector which is operable to collect corresponding backscattered light.
Related applications: WO2020CA51202