Julang Li

Key Research Areas
Associated Researchers
Associated Organizations

Recent Research Projects

Time-lapse imaging and software to monitor and predict embryonic health and viability

2019/20 • $130,500 • PI,CO
Canadian cattle industry generates over $ 40 billion annually, through direct and indirect revenue. While the Canadian dairy industry is a key driver of our national economy and represents one of the largest agri-food industries in the country, Canada's export of red meat and livestock is the...

Regulation of ovarian function

2015/16-2018/19 • $160,000 • PI
Canada’s pork industry produced 27 million pigs and exported 3.1 billion dollars of product worldwide in 2013. Reproductive efficiency is one of the key profitability components of the pork industry, however, compared to the more commonly used rodent models, our knowledge of ovarian physiology...

Toward commercialization of a novel fermentation product for enhancing intestine development and productivity of early-weaned pigs

2015/16-2017/18 • $270,000 • PI,CO
Digestive upsets and growth reductions of newly-weaned pigs are key concerns in pig management. Establishing an intestinal development-enhancing diet will help to optimize pig performance at this critical stage. To this end, we have generated epidermal growth factor (EGF) - expressing L. lactis,...

Purchase of an imaging multi-mode reader for animal bioscience research

2015/16 • $149,900 • PI,CO
<p>The Cytation 5 Imaging Multi-Mode Reader (C5-IMMR), produced by BioTek, is a state-of-the art fluorescent/luminescent plate reader combined with diverse imaging capabilities that allows for real-time physiological measurements of cells or tissues with simultaneous morphological imaging during...

Identification of metabolomic markers for on-farm selection of gilts with high reproductive potential

2015/16 • $25,000 • PI
The ability to identify highly reproductive gilts for recruiting into the breeding stock is one of the keys for profitable pork production. Currently, information on the sire and dam and all available relatives regarding reproductive performance, growth, and appearance are analysed. However,...

Regulation of ovarian follicular development and oocyte maturation

2010/11-2014/15 • $90,000 • PI
Understanding the mechanisms of ovarian follicular development and oocyte maturation may help to improve human and animal fertility. We have recently performed a set of preliminary experiments to study whether Glial cell line-derived neurotrophic factor (GDNF) may be involved in regulating...

Recombinant production of antimicrobial peptides as alternative to antibiotics

2013/14-2014/15 • $78,400 • PI
Antibiotic resistance in humans and animals is a growing concern for the public health in Ontario andworldwide. Searching for alternative effective means to overcome antibiotic resistance to treat emerginginfectious diseases is a new challenge. Protegrins (PGs) are a family of antimicrobial...

NSERC EmbryoGENE Strategic Network

2010/11-2013/14 • $3,452,850 • PI,CO
No summary

EGF expressing Lactococcus lactis (L.lactis) for enhancing intestine development, health, and productivity of early-weaned pigs

2010/11-2012/13 • $70,000 • PI,CO
Diarrhea and the associated reductions in growth rates during the period immediately after weaning is one of the major problems in nursery pig management. Developing a diet to stimulate intestinal development of early-weaned pigs may help to optimize their performance at this critical stage....

Germline potential of stem cells derived from skin

2010/11 • $46,105 • PI
Studying stem cell and their differentiation provides insights in the understanding of tissue development and help to identify factors that are important in this process. A recent report has provided evidence that female germ cells may be generated in postnatal ovary, raising the possibility...

Stem cell proliferation and genome stability:Impacts of microenvironment in vitro

2010/11 • $22,387 • PI
Being rare events in vivo, somatic stem cells are extensively expanded and propagated for stem cell research and applications. Unlike embryonic stem cells, which proliferate robustly, somatic cells are more difficult to expand in vitro. Attempts are being made to optimize culture environment...