Canada Research Chair in Developmental Neurobiology
Canadian Institutes of Health Research
- Grant type: Canada Research Chairs - CIHR Funded - Tier 2
- Years: 2010/11 to 2011/12
- Total Funding: $350,000
Miller, Freda D
Hospital for Sick Children
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No partner organizations found.
My research program focuses on determining how cells in the mammalian nervous system differentiate, survive, and establish connections during development, and on using this information to try and develop therapeutic strategies for treating the damaged or degenerating adult nervous system. Within this broad context, our specific objectives are to understand how growth factors maintain the survival and growth of developing and injured neurons, and to ask whether a novel accessible adult stem cell we have identified can be used to treat problems such as Parkinsons disease and spinal cord injury. This research program will hopefully provide us with therapeutic alternatives for nervous system disorders for which we currently have no treatments.
Overarching goal. Many mammalian tissues, including the brain, contain resident stem cells that build these tissues developmentally and maintain and/or repair them in adulthood. The biology of these tissue stem cells is determined by the interplay be... More ...
Each year, approximately 1000 Canadians sustain an acute traumatic spinal cord injury and join close to 40,000 paralyzed individuals across our nation who endure one of the most physically and psychologically devastating of injuries. We have recently... More ...
Organ failure is a pervasive medical problem that results in immense personal and economic costs, morbidity, and death. At present, the only truly effective treatment for organ failure is transplantation. The deficiencies of this option are increasin... More ...