Exciton Technologies

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Recent Research Projects

Investigating mechanisms of action of silver oxynitrate: an unexplored silver compound with superior anti-biofilm activity.

2017/18-2018/19 • $106,960
Silver has been used as an antimicrobial compound for thousands of years. Although interest in silver waned in the 1940s with the advent of antibiotic technologies, incidence of antibiotic resistance led to a resurgence in silver antimicrobial technologies in the 1980s. Since then, a variety of...

Elucidating biological targets of oxidized silver in fungal pathogens****

2018/19 • $25,000
Fungi are highly resilient microbiological eukaryotic microorganisms; rapidly adapting to various environments and external stressors, evolving resistance and exhibiting diverse strategies of pathogenesis. This combined with limited targets for selective fungicidal drugs has resulted in an...

Silver Oxysalt Impregnated Hydrogels

2015/16 • $25,000
Ag oxysaltsr is a novel antimicrobial silver technology but it is moisture and water sensitive. It is difficult to apply Ag oxysaltsr to any hydrogel matrix due to the long time that the formulation must stay in aqueous medium prior to use (ie during shipping, etc). This project will overcome...

Testing the efficacy of novel silver compounds for the eradication of multi species biofilms

2014/15 • $12,500
Bacteria often grow as a surface attached community referred to as a biofilm, which once formed, is protected from environmental stress. In the context of a human infection, this means a biofilm is more resistant to both the immune system and antibiotics. Additionally, biofilms are proposed to...

Molecular microbial ecology as a diagnostic tool to identify mode of action and new targets for oxidized silver wound dressings

2013/14 • $25,000
Chronic non-healing wounds considerably impact quality of life in affected patients and are a substantialburden on the Canadian health care system. Microbes colonizing a chronic wound play an important role inimpeding effective healing. Chronic wounds are colonized by polymicrobial communities...

Evaluating novel silver formulations for their antimicrobial efficacy towards biofilms

2013/14 • $24,900
Infection causing bacteria often grow as a surface attached community referred to as a biofilm, which onceformed, is protected from environment stress. In the context of a human infection, this means a biofilm is moreresistant to both the immune system and antibiotics. Additionally, biofilms are...

Silver oxysalt hydrogel: towards advanced silver antimicrobial coatings and medical devices

2010/11 • $25,000
Due to the growing concern over antibiotic resistance and the cost associated with bacterial infections related to medical devices, the search for novel bactericidal coating technologies is on the rise. The use of silver in bactericidal technologies offers a unique advantage over antibiotics,...

Lauren Huybregts

Scholarship/Fellowship 1

Lindsay Kalan

Scholarship/Fellowship 1

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