National Research Council Canada

Research Areas
Collaborating Researchers
Collaborating Organizations

Recent Research Projects

NSERC Canadian Floodnet

2014/15-2018/19 • $5,150,000
In Canada, floods are recognized as the most common, largely distributed natural hazard to life, property,economy, community/industry water systems, and the environment. The main objective of the proposedNSERC Canadian FloodNet is to create a vehicle for a concerted nation-wide effort to improve...

NSERC Energy Storage Technology Network

2015/16-2018/19 • $4,126,480
Electric grids comprising generation, transmission, and consumption will undergo a fundamental paradigmshift by introducing grid-scale energy storage (ES) systems. ES will be an invaluable asset for Canadianutilities who are facing intense pressures to provide clean, high quality, reliable and...

Flare emissions from unconventional oil and gas extraction and processing: An NSERC Strategic Network for cleaner fossil fuels

2016/17-2018/19 • $3,056,793
Emissions from flaring are a significant global concern. Satellite data suggest worldwide flared volumesexceed 140 billion m3 annually, where much of it is associated with development of unconventional oil andgas resources. In addition to being an important source of climate forcing CO2...

NSERC Network for Holistic Innovation in Additive Manufacturing (HI-AM)

2017/18-2018/19 • $1,933,750
Additive manufacturing (AM), also known as 3D printing, has been identified across sectors as the next generation technology that will fundamentally change manufacturing. AM is on the cusp of being widely adopted to replace many conventional manufacturing processes and enable the development of...

NSERC Green Surface Engineering for Advanced Manufacturing (Green SEAM) Network

2017/18-2018/19 • $1,933,750
The NSERC Green Surface Engineering for Advanced Manufacturing (Green-SEAM) Strategic Network is a far reaching collaborative research effort by leading Canadian researchers and their industry and government partners to position Canada as a world leader in emerging coating and surface...

NAIT Centre for Sensor and System Integration

2017/18-2018/19 • $875,000
The Centre for Sensors and System Integration (CSSI) provides industry, particularly small- andmedium-sized enterprises (SMEs), with prototyping, product enhancement, testing, and characterizationservices related to sensor and system integration. We also supply advanced testing services for...

Engendering success in STEM: a research consortium for gender equality in science and technology

2016/17-2018/19 • $706,516
Science and technology fields power the economy and provide highly rewarding careers, yet most of these jobs are held by men. Attracting more women to Science, Technology, Engineering, and Math (STEM) can address labour shortages, foster innovation through diversity, and counteract gender...

High efficiency and broadband fully integrated MMIC power amplifiers using GaN technology for space and terrestrial wireless communication

2016/17-2018/19 • $673,356
Research activities in the last decade have proven that the emerging Gallium Nitride (GaN) high-electron mobility transistors (HEMTs) are the superior technology choice for future designs of the power amplifier (PA), which is one the most challenging to design components in a wireless...

Quantum-secured communications for Canada (QSC2)

2017/18-2018/19 • $428,900
During the past decade, Canada has become deeply vulnerable to cyber attacks that undermine national security, economic prosperity, and the way of life of its citizens. Today, attacks mostly focus on stored information. Yet, current public key cryptosystems, created to protect information in...

21st century tools for Indigenous languages

2018/19 • $260,856
In response to the well-documented threats to Indigenous cultures and languages, this Partnership project will support the revitalization and sustained daily use of multiple Indigenous languages by developing modern technological tools and resources for these languages in collaboration with...

Partnership for the Organization of Innovation and New Technologies (4POINT0)

2017/18-2018/19 • $255,256
THE CHALLENGE: The fact that Canada's science and technology (S&T) performance is outstanding, while ranking near the bottom among OECD countries in terms of innovation performance, is a paradox that puzzles policy-makers and industry decision-makers. In addition to having difficulty translating...

Transparent armour ballistic performance modelling and optimization

2016/17-2018/19 • $246,000
A principal factor in the safety and effectiveness of the Canadian Armed Forces are advanced protectivestrategies for ballistic threats. Specifically, the enhancement of transparent armour for vehicle protection is essential for situational awareness while ensuring high mobility to manoeuvre...

Quantifying the Western Canadian marine energy resources and potential for large scale marine electricity production

2017/18-2018/19 • $71,536
For Pacific Canada, wave energy is a predominant renewable energy resource that has long been targeted for commercial development. Despite the prevalence of this renewable energy resource and a legislated mandates to exploit clean energy sources, wave energy does not appear in the BC Integrated...

21st century tools for Indigenous languages

2018/19 • $20,000
In response to the well-documented threats to Indigenous cultures and languages, this Partnership project will support the revitalization and sustained daily use of multiple Indigenous languages by developing modern technological tools and resources for these languages in collaboration with...

Developing biofilm-based microalgal bioreactors for the efficient production of fuels, chemicals and clean water

2014/15-2017/18 • $472,000
Using microalgae to convert carbon to biomass is one of the most promising technologies for developing renewable fuels. Algae produces more biomass than conventional crops such as corn and sugar beet, can be used to capture carbon and can be used in water treatment processes. Despite these...

Nanostructured ceramic coatings engineered for reduction of corrosion, erosion, fouling and viscous drag in industrial pipes and tubes

2015/16-2017/18 • $423,000
Steel structures such as reactor vessels, pipelines, boilers and industrial tubing are heavily used in the oil and gas industry, power generation, and in manufacturing for heating & transporting fluids. These structures are often subjected to erosion, corrosion and fouling effects. Erosion and...

Impact modeling of composite aircraft structures

2012/13-2017/18 • $365,140
This is a research and development project run under the CRIAQ industry driven project scheme. Its aim is to develop design methodologies and predictive numerical simulation methods for the high velocity impact response of composite aircraft structures. The focus is on developping enhanced...

Optimisation of fireproof, pressurized acoustic sandwich structures

2016/17-2017/18 • $300,000
The use of materials based on lightweight composite and aluminum, although common in other parts of the aircraft, remains a challenge around the engines because of the fire resistance prescribed by certification requirements. The present project focuses on the use of such materials for the...

Advanced thermal protection coatings

2015/16-2017/18 • $195,000
Thermal barrier coatings (TBCs) have been used in aircraft gas turbines for several decades. One of the early deposition methods for thermal barrier coatings , i.e. air plasma spray (APS), is still being used today for producing TBCs made of yttria-stabilized zirconia (YSZ). However these...

Application of UAV-borne LiDAR and Multispectral Imaging Technology for Accurate Classification and Inventory of Wetland Vegetation

2017/18 • $25,000
Fiera Biological Consulting Ltd. (Fiera) seeks to develop customized algorithms and workflows to automatethe assessment of wetland condition from Unmanned Aerial Vehicle (UAV) imagery. Achieving accurateassessments of wetland condition requires detailed and specialized input datasets that allow...

Partnership for the organization of innovation and new technology - 4POINT0: surf the wave or suffer the tidal wave - organise and understand disruptive innovation to better anticipate technology, economic and social mutations

2017/18 • $20,000
THE CHALLENGE: The fact that Canada's science and technology (S&T) performance is outstanding, while ranking near the bottom of the OECD members in terms of innovation performance, is somewhat of a paradox that is puzzling policy makers and industry decision-makers. The team of the proposed...

Catalysis Research for Polymer Electrolyte Fuel Cells (CARPE-FC)

2013/14-2016/17 • $4,000,000
Proton exchange membrane fuel cells (PEMFC) are being aggressively developed as clean energy conversiondevices. Promising near-term market applications include materials handling (e.g., fork lifts), backup power,residential co-generation, fleet vehicles (e.g., buses, taxis), and pOltable...

Wave Pump Application, Development and Optimization

2011/12-2016/17 • $2,296,290
The project aims at building a second generation prototype of the wave pump developed recently by our teamof researchers. The first of its kind in Canada, this simple yet innovative device is meant for pumping sea waterto on shore locations for a variety of applications; including aquaculture,...

NAIT Nanotechnology Centre for Applied Research, Industry Training, and Services

2011/12-2016/17 • $1,750,000
Although Alberta is home to Canada`s leading nanotechnology sector, the sector itself remains at an emergent stage. The Northern Alberta Institute of Technology (NAIT) proposes to create the Nanotechnology Centre for Applied Research, Industry Training, and Services (NanoCARTS). This Centre will...

Assessing the ecological risk of emerging nanomaterials- developing a generalized understanding based upon their physicochemical properties

2014/15-2016/17 • $492,000
Engineered nanoparticles (ENPs) are a rapidly expanding and diversifying group of technologies with current and potential applications in a range of industrial and domestic products including clothing, agriculture, electronics, healthcare and wastewater treatment. With increased application of...

Low power de-icing systems for light weight helicopters

2015/16-2016/17 • $245,500
Rotorcraft is vulnerable to rotor-blade in-flight icing. As so far only large helicopter may have rotor blades de-iced by means of high-energy electro-thermal systems, whereas small helicopter is lacking in the electrical power required to run them. That is why Bell Helicopter Textron, a...

NSERC - SENTINEL - Bioactive Paper Strategic Network

2010/11-2015/16 • $7,594,000
Bioactive paper that can detect and deactivate dangerous bacteria and viruses in food and water will deliver health benefits around the world. Bioactive Paper is a made-in-Canada concept articulated in the first phase (2005-2010) of the Sentinel Bioactive Paper Network, an NSERC strategic...

Projet d'amélioration de la performance de bioprocédés industriels par l'utilisation de consortiums de microorganismes

2010/11-2015/16 • $2,300,000
Le présent projet vise à améliorer la performance de certains bioprocédés industriels par la formulation de consortiums de microorganismes dont l'ajout bonifie les applications n'utilisant actuellement qu'une seule espèce de microorganismes. Un consortium de microorganismes est un mélange de...

Optimization and control of the new generation fuel system (NGFS) manufacturing process and the development of novel high pressure plastic fuel tank for hybrid systems

2012/13-2015/16 • $931,809
The Next Generation Fuel System (NGFS) process is a automotive tank manufacturing technology that combines the best attributes of both extrusion blow molding and thermoforming. The primary focus of this technology is to overcome limitations associated with current manufacturing technologies with...

Shot peening for fatigue life improvement of aerospace strutures

2012/13-2015/16 • $750,000
Shot peening is a cold working process widely used to improve the fatigue life of metal components in the aerospace industry. This process is accomplished by bombarding the surface of a metallic component with shots at a high velocity that induce a plastic deformation layer near the surface....

Design and analysis of hybrid joints (bonded and bolted) for aerospace structures

2012/13-2015/16 • $360,000
To make useful structures using composites materials, consideration must be given to the way structural components are joined together. The goal of this project is to develop an optimized design methodology for combined bolted and bonded joints for attaching composite structures. When analyzed...

Aqueous Chemistry of Metals under Supercritical Water Reactor Coolant Conditions

2011/12-2015/16 • $321,010
This proposal seeks funding for the second phase of a collaborative project that uses state-of-the-art instruments to determine ionization and association constants for simple acids, bases, dissolved metals, and metal complexes under near-critical and super-critical conditions that will be...

Development of Wind Uplift Standard For Roof Edge Systems and Technologies

2010/11-2015/16 • $281,000
Roof edge systems include components and its interface with the roof assembly. Technologies cover designt ools and test procedures.This proposal addresses Roof Edge Systems and Technologies and abbreviated as:REST. REST is the first line of defence for wind effects on roofs. In Canada, Built-Up...

Thermodynamics and mechanics of ice compressive failure

2013/14-2015/16 • $226,492
The Arctic contains a wealth of resources, and is believed to hold more than 20 percent of the world's undiscovered oil and gas. Canada encompasses a large share of arctic landmass and the longest coastline in the world, much of it in the arctic regions. There are vast resources, including oil,...

Intelligent robotic system for automated shot peening and peen forming

2012/13-2015/16 • $213,220
Shot peen forming (or SPF) and Shot peening (or SP) and are extensively applied in aerospace and transportation engineering to, respectively, form curved shapes from sheet metal (which would be difficult to form with traditional methods like stamping) and improve mechanical properties of the...

Dynamic properties of champlain sea clays

2013/14-2015/16 • $182,151
It is well-known that, in seismically-active regions of Eastern Canada, Champlain Sea sediments (or 'Leda Clays'), are particularly prone to amplified ground motions due to large impedance contrasts between soft soils and bedrock. However, the current knowledge on the variation of the dynamic...

Canadian Contribution to ILC Common Fund

2015/16 • $15,668
No summary

NSERC Strategic Network for the production of single-type glycoform monoclonal antibodies (Mabnet)

2010/11-2014/15 • $4,667,280
with an estimated annual growth of 14% up to 2012, based on the most recent economic analysis . Since 1996 there have been 20 approvals for Mabs to be used as therapeutics. Six of these are blockbusters with annual sales in excess of a billon dollars per year. This proposal addresses the...

NSERC Canadian network for research and innovation in machining technology (NSERC-CANRIMT)

2010/11-2014/15 • $4,598,700
The goal of the Network is the development of the worlds most advanced Virtual Machining Technology (VMT) for both macro and micro machining operations. This VMT will comprise a complete set of modeling and analysis tools for the planning of optimal machining operations in a virtual environment....

NSERC Smart Microgrid Network (NSMG-Net)

2010/11-2014/15 • $3,512,625
The NSERC Smart Microgrid Network (NSMG-Net) is developing technologies, in partnership with Canadian power utility companies, that will establish Canada's next generation electricity system, the Smart Grid. Comprised of a network of integrated intelligent Microgrids, Canada's Smart Grid will...

Nouvelle technologie de fabrication et réparation de roues de turbine hydrauliques et équipements connexes

2010/11-2014/15 • $1,978,340
L'hydroélectricité canadienne, moteur essentiel de l'économie, a l'avantage extraordinaire de disposer d'une ressource naturelle renouvelable. Le but de ce projet de recherche est de contribuer à l'utilisation responsable de cette ressource en mettant au point de nouvelles techniques de...

Polymères biorenouvelables pour l'industrie des plastiques et des composites

2010/11-2014/15 • $1,800,000
Le CEGEP de Thetford compte deux centres collégiaux de transfert de technologie, soit le CTMP (Centre de Technologie Minérale et Plasturgie) créé en 1993 et OLEOTEK (centre de recherche spécialisé en oléochimie industrielle) créé en 2002. À l'initiative du CEGEP de Thetford et afin de répondre...

Characterization of guided wave propagation in aircraft structures

2012/13-2014/15 • $558,320
Structural health monitoring (SHM) is a major area of interest for the aerospace community, especially considering aging aircraft where the growing maintenance costs estimated to $10,4 billion worldwide annually. The 5 to 10 years goal of the industry is to deploy SHM systems which will 1) meet...

A low cost / high power density gas turbine concept based on rotary ramjets

2012/13-2014/15 • $518,668
Developing clean mechanical power sources is strategic for developed countries to remain competitive in the years to come due to a constantly growing environmental pressure and stringent emissions regulations. This research develops a new type of gas turbine based on rotary ramjets for motive...

Aqueous Chemistry of Fission Products under Supercritical Water Reactor Coolant Conditions

2011/12-2014/15 • $200,000
This proposal seeks funding for the second phase of a collaborative project that uses state-of-the-art instruments to determine chemical equilibrium constants for simple acids, bases, dissolved metals, and metal complexes under the extreme conditions that will be encountered in the proposed...

Electrochemistry of Zn in ionic liquids

2012/13-2014/15 • $105,000
Public awareness of global warming resulting from green house gas emission has increased significantly in recent years. Much effort has been spent on promoting a low carbon economy. The electrification of surface transportation (e.g., electric vehicles and plug-in hybrid electric vehicles) will...

Pressure Sensing Mattress

2014/15 • $25,000
No summary

NSERC/Business Intelligence Network

2010/11-2013/14 • $4,137,050
The NSERC Business Intelligence Network will create an innovation platform to enhance the collaboration of the top Canadian knowledge and information management researchers and the top Canadian companies in business intelligence, an area that is central to NSERC's strategic Advanced...

NSERC Hydrogen Canada (H2CAN) Strategic Research Network

2010/11-2013/14 • $3,923,325
No summary

NSERC Magnesium Network (NSERC MagNET)

2010/11-2013/14 • $3,501,375
No summary

Programme de recherche appliquée et de transfert technologique en biotechnologie en soutien au développement socio-économique local et régional

2010/11-2013/14 • $1,557,628
La Cité collégiale est le premier et le plus important collège dMarts aookuqy.s et de technologie de langue française de l'Ontario. En 2003, le Collège lance un programme de baccalauréat en technologie appliquée - biotechnologie (B.T.A. - biotechnologie) d'une durée de 4 ans. Il devient le...

Novel tools for characterization of new drinking water disinfection byproducts and health effects

2011/12-2013/14 • $542,000
Emerging drinking water disinfection byproducts (DBPs) and other contaminants are a challenging public health issue because drinking water is a pervasive public exposure. The regulated DBPs offer no plausible toxicological explanation for increased risks of cancer and adverse health effects that...

ANR / Increasing oil content by redirecting carbon flux during seed development. Project acronym: SYNERGY (Seeds Yield eNERGY)

2011/12-2013/14 • $454,700
There are urgent environmental and economic pressures to develop renewable sources of energy. Biofuels represent an important component of such renewable energy provided that production does not compromise land use for food production and production costs are kept low. Biodiesel derived from the...

Mechanical behaviour of zirconia-based ceramics for use in CANDU supercritical water nuclear reactors

2010/11-2013/14 • $344,972
Canada's CANDU-Super Critical Water (SCW) reactor was selected by the Generation IV international forumas the next-generation nuclear power reactor. One of the primary objectives of this reactor will be tosustainably produce electricity at a reduced cost. In addition, the CANDU-SCW reactors will...

Autonomous collision avoidance system for small unmanned aerial vehicles.

2011/12-2013/14 • $230,000
The project develops the signal processing and control technologies required for small (less than 35 kg) unmanned aerial vehicles (UAVs) to satisfy new Transport Canada regulations to operate in non-segregated (civilian) airspace. The end product is a sense-and-avoid payload based on optical and...

NSERC Solid Oxide Fuel Cells Research Network

2010/11-2012/13 • $3,549,000
Fuel Cells efficiently and cleanly generate electrical power through the electrochemical oxidation of fuels. Solid Oxide Fuel Cells (SOFCs) are high temperature ceramic systems that offer significant advantages over other power sources, including the more well-known low temperature PEM Fuel...

CAtalysis Research for Polymer Electrolyte Fuel Cell (CARPE-FC)

2011/12-2012/13 • $1,000,000
Proton exchange membrane fuel cells (PEMFC) are being aggressively developed as clean energy conversion devices. Promising near-term market applications include materials handling (e.g., fork lifts), backup power, residential co-generation, fleet vehicles (e.g., buses, taxis), and pOltable...

NSERC Industrial Research Chair in Optical Design

2010/11-2012/13 • $600,000
No summary

NSC-Non-perfluorinated solid polymer electrolytes for fuel cell catalyst layers

2010/11-2012/13 • $277,500
Over the next 5 years the Canadian and world commercial demand for fuel cells will increase considerably. The Proton Exchange Membrane Fuel Cell sector accounts for the largest share of this market. Canadian technology manufacturers account for an impressive share of the international PEMFC FC...

Continuous Synthesis of Single-Walled Carbon Nanotubes with Thermal Plasma Technology / Synthèse continue de nanotubes de carbone monoparoi par la technologie des plasmas thermiques

2011/12-2012/13 • $256,843
Excellent physicochemical properties of single-walled carbon nanotubes (SWC NTs) make them good candidates for many applications ranging from lightweight materials for transportations to new catalytic supports for other functional materials. In a collaborative effort between the Université de...

Out of autoclave manufacturing of composite aerospace structures

2010/11-2012/13 • $250,000
The majority of aerospace composite structures are manufactured in autoclaves. Autoclave processing of composites uses primarily pre-impregnated unidirectional fibers or fabrics (prepreg) that are typically cured at 180 degree Celsius and consolidated with 6 atm of pressure. A large database of...

Optimum design of steered-tow composite structures via characterization of automated fibre placement induced defects

2010/11-2012/13 • $210,000
Automatic Fiber Placement (AFP) is an advanced technology for manufacturing composite structures of complex geometry. Boeing, Airbus and other world leading aircraft manufacturers have recently started to use this process for aviation products because its capability of automated fabrication...

Quality enhancement of roll formed woven fabric webs used in deck slabs

2010/11-2012/13 • $186,500
The application of textile composites in engineered products has been driven by their ease of formability from an original two-dimensional planar shape to complex three-dimensional shapes, along with the combination of light weight and high stiffness and strength. These attractive material...

Quantum Works - A Canadian quantum information network

2010/11-2011/12 • $1,560,490
No summary

Design and integration of nanostructured catalyst layers for PEM fuel cells

2010/11-2011/12 • $382,760
The deployment of cost-competitive, highly efficient, and environmentally benign energy conversion technologies is a major global challenge. In spite of excellent technological prospects, commercialization of Polymer Electrolyte Fuel Cells (PEFCs) in transportation, electronics, and stationary...

Micromachined electrodes and integrated circuits for implantable cortical brain interfaces

2010/11-2011/12 • $336,000
One billion people worldwide are affected by neurological disorders. The economic cost of neurological disorders comprises 28 percent of the economic cost of all diseases in Canada. In many patients with neurological disorders, drug therapy has failed or proved to be inefficient. Lack of...

Structure and chemistry of new nanomaterials for PEMFC

2010/11-2011/12 • $319,800
This proposal aims to contribute to the development of new generations of materials for Proton Exchange Membrane Fuel Cells (PEMFC) as part of the $10M Technology Development Project (TDP) of the NRC jointly with Ballard and AFCC. More specifically, the proposed research will focus on the...

Printable low-cost transistors based on poly (2,7-carbazole) derivatives

2010/11-2011/12 • $200,000
Conjugated polymers combine the interesting electrical and optical properties of traditional semiconductors with the processing advantages and mechanical properties of traditional synthetic polymers. This research field is aiming to set up the so-called plastic electronics where micro-electronic...

Green Crop Network

2010/11 • $813,187
No summary

Converting low value biomass into hydrogen

2010/11 • $156,900
The continued growth of the Canadian (and global) population seems to disproportionately increase the demands on the nation's natural resources and ultimately results in the development greater quantities of waste byproducts. The reuse of biomass to generate a renewable energy source is of...

Development of high temperature aluminum alloys for automotive diesel engine applications

2010/11 • $136,000
This project proposal is for the development of new aluminum alloys with improved high-temperature performance (creep resistance, strength, ductility, thermal fatigue resistance and castability) as well as acceptable cost to be used in automotive Diesel engine applications for vehicle weight...

Tissue engineered vascular grafts from nonwoven fibrous structures

2010/11 • $125,000
Vascular diseases are the first cause of hospitalization in industrialized countries. Their total cost to the Canadian economy is estimated at $19 billion. Current therapies to treat occluded vessels include surgical bypass and autologous grafting, or implantation of intravascular stents. Both...

The efficient application of thermoplastic composites to a light helicopter tail boom

2010/11 • $120,000
This project aims at the development of tapered thermoplatic composite tail booms for helicopters which has the configuration of a tapered cylinder. It connects the cabin of the helicopter to the tail rotor, whose function is to control the direction and stability of the aircraft. The tail boom...

Determination of the impact of wastewater disinfection processes on the virulence risk of Eschericia coli.

2010/11 • $113,309
The availability of safe, clean water is an essential security element for Canadians. Urban populations generally rely on surface waters (rivers and lakes) for their drinking water supplies, but these same waters often receive effluent discharges from municipal wastewater treatment plants....

Integrated terahertz frequency generator

2010/11 • $86,000
Terahertz radiation, in the range of 100 GHz to 30 THz, has been investigated for astronomy and analytical science. Recent advancements in photonics and nanotechnology are now enabling innovative research of new THz generation technologies. One technique for terahertz radiation is to use...

Nanosystems in transplantation: blood group antigens as immunologic tolerogens for infant heart transplantation

2010/11 • $65,614
Nanosystems in Transplantation: Blood group antigens as immunologic tolerogens for infant heart transplantation In heart transplantation, blood group matching between donor and recipient is necessary to prevent a rapid form of rejection called 'hyperacute' rejection, which results in loss of the...

Distributed control design for multi-agent systems and cooperative robots

2010/11 • $37,600
Future civilian and military rescue missions will rely on large, networked groups of small vehicles and sensors operating in dynamic, resource-constrained, adversarial environments. Groups of this type will typically operate with little or no direct human supervision and will be very difficult,...

Canada-EU Future Internet Workshop

2010/11 • $24,861
The Canada-EU Future Internet Workshop 2011 will bring together EU and Canadian researchers and companies to explore opportunities to directly interact, to be updated on the respective research statuses, and to explore areas of mutual interest. The event is designed to address industry interests...

PERISTALTIC PUMP MICROFLUIDIC SEPARATOR

McGill University, National Research Council Canada

A technique for separating components of a microfluid, comprises a self-intersecting micro or nano-fluidic channel defining a cyclic path for circulating the fluid over a receiving surface of a fluid component separating member; and equipment for applying coordinated pressure to the channel at a plurality of pressure control areas along the cyclic path to circulate the fluid over the receiving surface, applying a pressure to encourage a desired transmission through the separating member, and...

APPARATUS AND METHOD FOR CONTROLLING VARIABLE POWER CONDITIONS IN A FUEL CELL

National Research Council Canada, University of British Columbia

A fuel cell comprises an anode having an inner face and an outer face fluidly communicable with a fuel; a cathode having an inner face ionically communicable with and physically separated from the anode inner face, and having an outer face fluidly communicable with an oxidant; and at least one movable guard movable over at least one of the anode outer face, cathode outer face, anode inner face, and cathode inner face. The guard has a structure sufficient to block at least part of one or more...

TWO- AND THREE-TERMINAL MOLECULAR ELECTRONIC DEVICES WITH BALLISTIC ELECTRON TRANSPORT

National Research Council Canada, University of Alberta

Two- and three-terminal molecular electronic devices with ballistic electron transport are described. For example, a two-terminal molecular electronic device includes a conductor 1 layer/molecule 1 layer/conductor2 layer junction, wherein the total thickness of the molecule 1 layer and the conductor2 layer is less than or approximately equal to the mean free path of a charge carrier traveling in the two layers, and wherein ballistic transport can occur for some fraction of a plurality of...

METHOD FOR ORGANIZING A BLOCK COPOLYMER

National Research Council Canada, University of Alberta

The present disclosure includes a method for organizing a block copolymer (BCP) comprising contacting a substrate with the block copolymer, and exposing the BCP-coated substrate to a suitable energy source under conditions sufficient to induce substrate heating and organize the block copolymer.

ATOMISTIC QUANTUM DOTS

National Research Council Canada, University of Alberta

A quantum device is provided that includes controllably quantum mechanically coupled dangling bonds extending from a surface of a semiconductor material. Each of the controllably quantum mechanically coupled dangling bonds has a separation of at least one atom of the semiconductor material. At least one electrode is provided for selectively modifying an electronic state of the controllably quantum mechanically coupled dangling bonds. By providing at least one additional electron within the...

SYSTEMS AND METHODS FOR INJECTING FLUID INTO BONE AND FOR INSERTING BONE SCREWS, AND BONE SCREWS FOR SAME

McGill University, National Research Council Canada

Systems and methods for the insertion of bone screws and for fluid injection using bone screws are described. A bone screw used for fluid injection includes a screw body with a central passage extending at least partially into the screw body and defining an inlet end which includes an opening configured to matingly receive therein an injector tip of a fluid injector. The screw body includes a number of fluid flow passages extending through the screw body wall such as to direct fluid in an...

RADIOFREQUENCY RADIATIONG DEVICE

National Research Council Canada, University of British Columbia

A technique for coupling guided radiofrequency electromagnetic waves with free-space radiofrequency electromagnetic radiation comprises providing a plurality of coaxial waveguides, each for guiding TE11 mode of a respective band of wavelengths coupled from the free-space radiofrequency electromagnetic radiation, wherein the coaxial waveguides are separated by one or more walls running substantially parallel to an axis of the coaxial waveguides; providing a single, mechanically continuous,...

METHOD OF FABRICATING NANO-TIPS WITH CONTROLLED PROFILE

National Research Council Canada, University of Alberta

A nanotip, is fabricated by modifying a precursor nanotip having an apex and a shank by applying an electric field in the presence of a reactive gas to perform field-assisted etching wherein atoms are preferentially removed from the shank by chemical interaction with the reactive gas, and controlling the reactive gas pressure and/or tip voltage to vary the electric field so as to promote field evaporation of apex atoms during fabrication of the nanotip and thereby control the overall profile...

PRESSING APPARATUS FOR MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY

National Research Council Canada, SUNNYBROOK RESEARCH INSTITUTE

A magnetic resonance (MR) apparatus, the MR apparatus including a tissue pressing surface having one or more MR coil elements, the pressing surface being configured and sized to selectively indent a portion of an exterior tissue of a subject when a physical force is applied to the indenting substrate thereby reducing a distance between the one or more MR coil elements and a structure of interest located inside the subject.

OPHTHALMIC DEVICES AND RELATED METHODS AND COMPOSITIONS

COOPERVISION, COOPERVISION INTERNATIONAL HOLDINGS, LP, National Research Council Canada, Ottawa Health Research Institute

Devices, methods, and compositions for improving vision or treating diseases, disorders or injury of the eye are described. Ophthalmic devices, such as corneal onlays, corneal inlays, and full-thickness corneal implants, are made of a material that is effective in facilitating nerve growth through or over the device. The material may include an amount of collagen greater than 1% (w/w), such as between about 10% (w/w) and about 30% (w/w). The material may include collagen polymers and/or a...

ELECTROSTATICALLY REGULATED ATOMIC SCALE ELECTROCONDUCTIVITYDEVICE

National Research Council Canada

La présente invention a trait à un dispositif d'électroconductivité à l'échelle atomique à régulation électrostatique comportant une espèce de perturbation ayant une charge électronique localisée. Une espèce de détection ayant une conductivité électronique est disposée à proximité de l'espèce de perturbation à une distance suffisante pour induire une modification dans la conductivité électronique associée à la charge électronique localisée. Des dispositifs électroniques sont prévus pour la...

PEPTIDES AND METHODS AND USES THEREOF FOR MODULATING ANAPHASE PROMOTING COMPLEX (APC) ACTIVITY

National Research Council Canada, University of Saskatchewan

Novel activators of the APC complex and methods and uses of these activators are provided. In particular, the activators are used for increasing resistance to stress and/or increasing lifespan in a plant or mammalian cell, in a plant or mammalian embryo or in a plant or subject. The activators are also used for treating cancer in a subject.

D-GLYCERO-B-D-HEPTOSE 1-PHOSPHATE (HMP) CONJUGATES AND USE FOR TARGETED IMMUNE MODULATION

National Research Council Canada, University of Toronto

Heptose-1-monophosphate-7-derivatives are modifiable immunomodulators that can be used to prepare clinically active conjugate compounds. Such conjugate compounds are useful in modulating an immune response in a subject.

SAPONIN EXTRACT FROM <i

National Research Council Canada, NATIONAL RESEARCH COUNSIL OF CANADA, University of Saskatchewan

A saponin extract from Saponaria vaccaria and its use for stimulating apoptosis in cancer cells and treating cancer is described. The saponin extract may be isolated from Saponaria vaccaria seed. The saponin extract may comprise one or more than one triterpene saponin. The triterpene saponin may comprise a bisdesmosidic saponin having a molecular weight selected from the group consisting of molecular weight 1448, 1464, 1422, 1526, 1596 and 1688. Bisdesmosidic saponin of molecular weight...

CELL-BASED PRODUCTION OF NONULOSONATES

National Research Council Canada, University of Ottawa

The present invention relates to the cell-based production of bacterial nonulosonates and their biosynthetic precursors. Specifically, the present invention provides recombinant cells for the production of pseudaminic acid, legionaminic acid, UDP-2,4-diacetamido-2,4,6-trideoxy-ß-L-altropyranose, and UDP-2,4-diacetamido-2,4,6-trideoxy-a-D-glucopyranose. Methods for producing the sugars are also provided.

SELF-ASSEMBLING PEPTIDE FOR ACTIVATING HUMAN MAST CELLS

National Research Council Canada, University of Alberta

The present disclosure relates to bioactive self-assembling peptides, nanofibers and hydrogels for activating human mast cells. The peptides, nanofibers and hydrogels comprise a self-assembling peptide that mediates self-assembly linked to a MrgX2 agonist peptide; for example, (RADA)4 linked to proadrenomedullin-12 (PAMP-12).

APPLE SKIN EXTRACTS FOR TREATING CARDIOVASCULAR DISEASE

Dalhousie University, HER MAJESTY THE QUEEN IN RIGHT OF THE PROVINCE OF, National Research Council Canada

Pharmaceutical and nutraceutical compositions and methods for treating cardiovascular disease, comprising apple skin extracts which can reduce cholesterol levels and inhibit low density lipoprotein (LDL) oxidation in a subject, are provided.

DNA SEQUENCES ENCODING CARYOPHYLLACEAE AND CARYOPHYLLACEAE-LIKE CYCLOPEPTIDE PRECURSORS AND METHODS OF USE

National Research Council Canada, NATIONAL RESEARCH COUNSIL OF CANADA, University of Saskatchewan

Naturally-occurring and modified recombinant nucleic acid molecules have been isolated that encode linear precursors of cyclopeptides of the Caryophyllaceae (Ccps) and Caryophyllaceae-like (Clcps) type Vl class of cyclopeptides. Such nucleic acid molecules are useful for producing cyclopeptides and their linear precursors by recombinant methods.

NANOTUBES AND COMPOSITIONS THEREOF

Brown University, NATIONAL RESEACH COUNCIL OF CANADA, National Research Council Canada, University of Alberta

The present invention is directed to implants and the modification of the surface of implants using amino acid or polypeptide functionalized rosette nanotubes.

SOLUBLE IGF RECEPTOR FC FUSION PROTEINS AND USES THEREOF

McGill University, National Research Council Canada

There are described herein novel soluble IGF receptor Fc fusion proteins and compositions and methods of use thereof for treating angiogenesis associated disorders and malignant disease, such as cancer and metastasis, wherein the fusion proteins bind specifically to IGF-1 or IGF-2.

ANTI-APOPTOTIC PROTEIN ANTIBODIES

National Research Council Canada, University of Windsor

Single-domain antibodies that bind pro-apoptotic proteins Bax and caspase-3 are identified and isolated. These single-domain antibodies may be used to modulate the activity of Bax and caspase-3, thereby modulating the symptoms and steps of oxidative stress and/or cell apoptosis, including Bax dimerization, mitochondrial permeabilization and the release of apoptotic proteins.

IDENTIFICATION OF IMMUNOGLOBULIN (IG) DISORDERS USING FOURIER TRANSFORM INFRARED SPECTROSCOPY

National Research Council Canada, University of Prince Edward Island

A method and a corresponding system for obtaining a serum mid-infrared spectroscopic profile using Fourier-transform infrared spectroscopy (FTIR) a re described. The method comprises acquiring FTIR spectra for dried sera and preprocessing the FTIR spectra of sera by differentiation and smoothing to enhance weak spectral features and to remove baseline variations. The preprocessed FTIR spectra are normalized to a common intensity range, the normalization being performed in a spectral sub-...

MEMBRANELESS FUEL CELL AND METHOD OF OPERATING SAME

National Research Council Canada, University of British Columbia

A direct fuel cell comprises a cathode comprising electroactive catalyst material; and an anode assembly comprising an anode having a porous layer an d electroactive catalyst material in the porous layer. The electrode charact eristics of the anode assembly are selected so that fuel supplied to the ano de is reacted within the anode so that cross-over from the anode to the cath ode does not have more than a 10% negative effect on voltage or a 25 mV volt age loss when at peak power and steady...

CLIPPED AMPLIFIER

National Research Council Canada, University of Alberta

ABSTRACT OF THE DISCLOSURE A clipping circuit for an amplifier, the clipping circuit using a tunneling junction. A molecular or other tunneling electronic-based component within a hybrid analog-tunneling circuit is used to produce soft or hard clipping capability with enhanced control over the output. The circuit may be used as a distortion circuit for an electric guitar signal or other electronic signals.

GENES AND PROTEINS FOR ALKANOYL-COA SYNTHESIS

National Research Council Canada, University of Saskatchewan

Polypeptides having alkanoyl-CoA activity have been identified and characterized, as have nucleic acids encoding these polypeptides. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.

PHOTOVOLTAIC DEVICE BASED ON CONFORMAL COATING OF COLUMNAR STRUCTURES

National Research Council Canada, University of Alberta

A photovoltaic device, comprises a first electrode, an electron donor layer in electrical contact with the first electrode, an electron acceptor layer in contact with the electron donor layer across an interface having a shape defined by a columnar structure grown by oblique angle deposition, and a second electrode in electrical contact with the electron acceptor layer.

DEVICES WITH FLAT CONDUCTING SURFACES

National Research Council Canada, University of Alberta

An electronic device may have one or more intermediate layers between contacts each comprising an e-beam deposited carbon (e-Carbon) layer and a metal layer. The e-Carbon layers may be contacting the adjacent intermediate layers. The one or more intermediate layers may comprise a molecular or oxide layer. One or more of the contacts may be sufficiently thin to allow at least partial transparency to light. The device may be deposited on a flexible substrate and be sufficiently thin to allow...

GENES AND PROTEINS FOR AROMATIC POLYKETIDE SYNTHESIS

National Research Council Canada, University of Saskatchewan

Nucleic acid molecules encoding polypeptides having polyketide synthase activity have been identified and characterized. Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds in organisms. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.

FUNCTIONALIZED SEMICONDUCTING POLYMERS FOR USE IN ORGANIC PHOTOVOLTAIC DEVICES

National Research Council Canada, University of Alberta

The present invention is directed to functionalized semiconducting polymers (FSPs) having the following general formula (I): wherein PB is a semiconducting polymer backbone, L is an alkyl, alkenyi or alkoxy chain and CTG is a cationic terminal group. The FSPs may be used as interfacial modifiers in organic electronics, and more specifically organic photovoltaic devices.

USE OF FLUORINATED CYCLIC DINUCLEOTIDES AS ORAL VACCINE ADJUVANTS

Brock University, National Research Council Canada

Disclosed is the use of fluorinated cyclic dinucleotides and pharmaceutically acceptable salts thereof as an adjuvant for the preparation of an oral vaccine. Further disclosed is the use of fluorinated cyclic dinucleotides and pharmaceutically acceptable salts thereof for enhancing the immune response to an orally administered vaccine.

METHODS OF TAILORING ELECTRODE WORK FUNCTION USING INTERFACIAL MODIFIERS FOR USE IN ORGANIC ELECTRONICS

National Research Council Canada, University of Alberta

The present invention is directed to methods for tailoring the work function of electrodes in organic electronics using interfacial modifiers comprising functionalized semiconducting polymers and/or small molecules.

DE-ICING SYSTEM AND METHOD

National Research Council Canada, Université du Québec à Chicoutimi

Ice formation is removed by inducing mechanical vibrations in the audible range of frequencies, where the mechanical vibrations are of an amplitude sufficient to cause ice-expelling strain deformation.

SYSTEM AND METHOD FOR SURFACE PLASMON RESONANCE BASED DETECTION OF MOLECULES

INDUSTRIAL MATERIALS INSTITUTE, NATIONAL RESEARCHCOUNCIL CANADA, McGill University, National Research Council Canada

A system and method for molecule detection uses a surface plasmon resonan ce (SPR) system with detection spots having fixed nanostructures. An SPR ass embly may be combined with a digital microfluidic control system such as an electrowetting-on-dielectric (EWOD) chip. The microfluidic system individual ly directs sample droplets to different detection spots of the SPR assembly, thus allowing the SPR examination of different samples or sample reactions on the same surface. The nanostructures...

USE OF PHOSPHORYLATED HEPTOSE COMPOUNDS

National Research Council Canada, University of Toronto

Phosphorylated heptose compounds are useful in modulating an immune response in a subject. Also, the compounds are useful as adjuvants.

AROMATIC PRENYLTRANSFERASE FROM CANNABIS

National Research Council Canada

Nucleic acid molecules from Cannabis sativa (cannabis, hemp, marijuana) ha\ e been isolated and characterized, and encode polypeptides having aromatic prenyltransferase activiity. Specifically, the enzyme, CsPT1, is a geranylpyrophosphate olivetolate geranyltransferase, active in the cannabinoid biosynthesis step of prenylation of olivetolic acid to form cannabigerolic acid (CBGA). Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds. The polypeptides may...

SOLUBILIZED FORMULATION OF COQ10 FOR USE IN TREATMENT OF PARKINSON'S DISEASE

National Research Council Canada, NATIONAL RESEARCH COUNCIL OF CANADA (NRC), University of Windsor

Provided herein are compositions and methods for reducing neurogeneration in a patient suffering from Parkinson's Disease, comprising administration of a composition comprising CoQ10 and polyoxyethanyl-a-tocopherylsebacate (PTS). The compositions of the invention have been shown to penetrate the blood-brain barrier in mammals, thus effecting delivery of CoQ10 directly to brain tissue. Beneficial effects of the treatment have been observed at lower doses of CoQ10 than previously described.

IN VITRO MODEL OF FOCAL ISCHEMIA

National Research Council Canada, University of Prince Edward Island

A method of modeling in vitro focal ischemia comprising: perfusing a tissue slice in vitro with an oxygenated medium; and, applying a focal insult to a targeted portion of the tissue slice. The method is particularly useful for brain tissue.

TREATING A SILICON ON INSULATOR WAFER IN PREPARATION FOR MANUFACTURING AN ATOMISTIC ELECTRONIC DEVICE INTERFACED WITH A CMOS ELECTRONIC DEVICE

National Research Council Canada, Quantum Silicon, University of Alberta

The invention relates generally to integrated circuit electronics, particularly to methods for integrating CMOS electronics and atomistic electronics.