MODULATORS OF AMPA RECEPTOR SIGNALING

Contacts

Contact Centre for Addiction and Mental Health

Inventors
  • LIU, Fang
  • GREIG, Iain
  • ZHAI, Dongxu
  • SMITH, Stephen Allan
  • ZANATO, Chiara
  • TSENG, Chih-Chung
Documents
Applicants
  • Centre for Addiction and Mental Health
  • THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN

Abstract

The present disclosure relates to compounds of the Formula (I) which have shown utility in modulating AMPA receptor signaling and thus preventing AMPA receptor-mediated toxicity, which may find use in the treatment of diseases in which AMPA receptor activation plays a role in neurodegeneration, including the treatment of multiple sclerosis and other diseases.