APTAMERS AS A THERAPEUTIC TOOL TO PREVENT PROTEIN AGGREGATION IN NEURODEGENERATIVE DISEASE

Inventors
  • DEROSA, Maria Cynthia
  • HOLAHAN, Matthew Richard
  • MCCONNELL, Erin Marie
  • VENTURA, Katelyn Victoria
  • CALLAHAN, Joshua Parker
  • HUNT, Vernon Harold Daniel
Documents
Applicants
  • Carleton University
Contact Info
Theresa White
Manager, Contracts and Agreements, Industry and Partnerships Services
(613) 520-2600
[email protected]

Abstract

The present disclosure relates generally to the selection of DNA aptamers that prevent aggregation, or fibrilization of alpha-synuclein protein. The aptamers described herein are of use as a therapeutic tool to prevent protein aggregation in neurodegenerative disease.