14-3-3 eta antibodies and uses thereof for the diagnosis and treatment of arthritis
Inventors
- MAROTTA, Anthony
Documents
- AU2008329466
- AU2008329529
- CA2008002094
- CA2008002154
- CA2706476
- CA2706479
- CN200880125674
- CN200880125676
- CN201711119889
- EP08853323
- EP08855660
- EP17159000
- EP17159003
- HK11105914
- HK18112716
- IL20594810
- IL25415717
- JP2010534331
- JP2010534332
- JP2014109818
- JP2014236075
- JP2017039151
- KR20107014288
- KR20107014289
- KR20167029986
- KR20177027282
- KR20187025773
- US14798398
- US14873157
- US74522908
- US74523508
Applicants
- KILANI, RUHANGIZ
- MAROTTA, ANTHONY
- University of British Columbia
- GHAHARY, AZIZ
- MAKSYMOWYCH, WALTER, WOLODYMYR, PETER
Contact Info
Abstract
14-3-3 eta antibodies and uses thereof for the diagnosis and treatment of arthritis are provided. The invention provides anti-14-3-3 eta antibodies that specifically bind to the human 14-3-3 eta protein isoform in its natural configuration while exhibiting selectivity over human 14-3-3 alpha, beta, delta, epsilon, gamma, tau, and zeta protein isoforms. Methods, kits and pharmaceutical compositionscomprising said specific anti-14-3-3 eta antibodies are further provided for the diagnosis and treatment of arthritis.